Table 4.

Use of OTC NSAIDs per risk group within the high-risk sample

Total invited, nTotal participants n (% of invited)OTC NSAID used n (% of participants)
Total number of patientsa713264 (37)33 (13)
High gastrointestinal risk662249 (38)31b (12)
  History of peptic ulcer/UGI complication16346 (28)7 (15)
  Age >70 years309110 (36)8 (7)
Two or more minor risk factors361149 (41)18 (12)
  Use of anticoagulant7231 (43)1 (3)
  Use of aspirin288118 (41)11 (9)
  Use of corticosteroid5721 (37)3 (14)
  Use of SSRI4913 (27)1 (8)
  Age 60–70 years254117 (46)16 (14)
  Severe rheumatoid arthritis145 (36)0 (0)
  Heart failure11737 (32)6 (16)
  Diabetes mellitus12245 (37)8 (18)
High cardiovascular risk305115 (38)14 (12)
  History of myocardial infarction13148 (37)5 (10)
  History of stroke8938 (43)5 (13)
  Heart failure11737 (32)6 (16)
High renal risk: chronic renal insufficiency378 (22)2 (25)
  • UGI = upper gastrointestinal. NSAID = non-steroidal anti-inflammatory drug. OTC = over-the-counter. SSRI = selective serotonin reuptake inhibitor.

  • a Each patient can potentially have more than one risk factor.

  • b Of which 5 (16.1%) had been prescribed a proton pump inhibitor in 3 months prior to selection.