Logistic regression analysis on predictors for antibiotic prescription in patients with suspected M. pneumoniae corrected for multilevel (n = 176), case–control study in Vestfold, Norway, 2011
| Factor | (n in bivariate analysis) | Bivariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | ||
| Pulmonary findings | Normal (ref) (n = 301) | 1 | 1 | ||
| Wheezing (n = 28) | 0.5 (0.2 to 1.0) | 0.053 | 0.5 (0.2 to 1.5) | 0.23 | |
| Crackles (n = 64) | 6.2 (2.3 to 17.0) | <0.001 | 5.6 (1.2 to 25.4) | 0.007 | |
| General condition | Good (ref) (n = 212) | 1 | 1 | ||
| Moderately affected (n = 168) | 4.6 (2.9 to 7.1) | 0.004 | 2.9 (1.6 to 5.1) | <0.001 | |
| Severely affected (n = 10) | 13.7 (2.8 to 66.5) | <0.001 | 6.3 (1.3 to 31.1) | 0.023 | |
| CRP value | <8 (ref) (n = 140) | 1 | 1 | ||
| 8–22 (n = 96) | 1.8 (1.0 to 3.5) | 0.04 | 0.7 (0.3 to 1.4) | 0.3 | |
| >22 (n = 116) | 5.7 (3.3 to 9.9) | <0.001 | 2.4 (1.3 to 4.5) | 0.007 | |
| Temperature>38.0°C | No (ref) (n = 116) | 1 | 1 | ||
| Yes (n = 216) | 3.1 (2.6 to 6.1) | <0.001 | 2.7 (1.4 to 5.2) | 0.005 | |
The following findings were associated in the bivariate analysis, but not significantly associated in the multivariate analysis: age and presence of cough. CRP = C-reactive protein. Ref = reference.