Table 4.

Differences in QOF CVD prescribing targetsa by serious mental illness status adjusted for sociodemographic characteristics and primary care consultation frequency

Reference (non-SMI)Unadjusted OR (95% CI)Adjusted for sociodemographics ORb (95% CI)Additionally adjusted for consultation rate ORc (95% CI)
Beta blocker
  After CHD1.000.62 (0.41 to 0.93)d0.68 (0.44 to 1.05)0.66 (0.42 to 1.01)
  After HF1.000.29 (0.16 to 0.53)f0.29 (0.15 to 0.55)f0.27 (0.14 to 0.52)f
ACEI/ARB
  After CHD1.000.59 (0.36 to 0.97)d0.55 (0.33 to 0.94)d0.47 (0.27 to 0.80)e
  After HF1.000.33 (0.18 to 0.61)f0.34 (0.18 to 0.66)f0.31 (0.16 to 0.60)f
Antiplatelet/anticoagulant
  After CHD1.000.95 (0.54 to 1.65)1.04 (0.57 to 1.89)0.94 (0.51 to 1.73)
  After STIA1.001.04 (0.68 to 1.60)0.99 (0.62 to 1.59)1.04 (0.64 to 1.69)
Statin
  After CHD1.000.76 (0.45 to 1.28)0.78 (0.45 to 1.36)0.70 (0.40 to 1.23)
Quadruple therapyg
  After CHD1.000.65 (0.40 to 1.06)0.62 (0.37 to 1.04)0.28 (0.34 to 0.98)d
  • ACEI/ARB = angiotensin-converting enzyme inhibitor/angiotensin receptor blocker. CHD = coronary heart disease. CVD = cardiovascular disease. HF = heart failure. OR = odds ratio. QOF = Quality and Outcomes Framework. SMI = severe mental illness. STIA = stroke/ transient ischaemic attack.

  • a Refers to QOF guidelines 2012/13.17

  • b Adjusted for age (continuous), sex, ethnic group, and borough-level deprivation.

  • c Additionally adjusted for mean annual number of primary consultations.

  • d P <0.05.

  • e P <0.01.

  • f P <0.001.

  • g Quadruple therapy indicated in patients with history of myocardial infarction and includes statin, antiplatelet/anticoagulant, beta blocker, and ACEI/ARB medication.