Comparison of inflammatory markers in the year before diagnosis
| Blood test | Blood test results | Odds ratio (95% CI) | P-value | LR+ (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
| Cases | Controls | |||||||
| Number tested,a n | Abnormal (%) | Normal (%) | Abnormal (%) | Normal (%) | ||||
| ESR | 2192 | 844 (85) | 154 (15) | 546 (46) | 648 (54) | 5.7 (4.1 to 8.0) | <0.001 | 1.9 (1.7 to 2.0) |
| CRP | 1274 | 294 (46) | 341 (54) | 238 (37) | 401 (63) | 1.5 (1.0 to 2.2) | 0.05 | 1.2 (1.1 to 1.4) |
| PV | 433 | 162 (81) | 39 (19) | 95 (41) | 137 (59) | 4.4 (2.2 to 8.8) | <0.001 | 2.0 (1.7 to 2.3) |
↵a Sample size corresponds to the number of patients who had the test or a particular combination of tests. CRP = C-reactive protein. ESR = erythrocyte sedimentation rate. LR+ = positive likelihood ratio. PV = plasma viscosity.