Table 2.

Effectiveness of two strategies of case finding women with a history of ovarian cancer in primary care for genetic counselling and DNA testing

EffectivenessCase finding strategy, n (%)
Patients with OC identified3094
Eligible for CG referral according to GPa19 (63)39 (41)
Approached for referral by GPb15 (79)33 (85)
Consulted GP and referredc8 (53)8 (24)
EOC patients seen by CGd5 (63)5 (63)
Genetic predisposition detected10
  • a In strategy A, 11 patients were considered not eligible for CG referral because they had ‘already consulted CG’. In strategy B, reasons that 55 patients were ineligible for referral included: ‘already consulted CG’ (10 patients), ‘no longer in GP practice’ (13 patients), ‘deceased’ (25 patients), and ‘other reason’ (7 patients), including false-positive diagnostic codes.

  • b In strategy A, 4 patients who were eligible were not approached by the GP because it would be emotionally too burdensome, patient had dementia, patient had wrong tumour pathology (mucinous borderline, mucinous cystadenoma, reason unknown: all 1 patient). In strategy B, 6 patients who were eligible were not approached because the GP stated they had already been referred for CG.

  • c Of the 48 patients approached for GP consultation and referral, 32 did not comply or follow-up was not registered; for 16 patients the GP did not report on their acceptance or decline of invitation and referral, 12 declined the invitation for unknown reasons, 3 patients were previously referred for GCT, 1 left the GP practice.

  • d Reasons for accepted referral but not seen by CG (6 patients): 3 patients were not eligible for follow-up by CG because of borderline ovarian cancer and granulosa cell tumour; 3 patients cancelled the CG consultation for unknown reasons. CG = clinical geneticist. EOC = epithelial ovarian cancer. OC = ovarian cancer.