Demographic characteristics of patients at the beginning and at the end, persistence of treatment, and new patients with treatment, by control and intervention groups
| Total, n | Control group | Intervention group | P- value | Difference,% (95% CI) | |
|---|---|---|---|---|---|
| Patient characteristics at baseline | |||||
| Patients, n (%) | 1932 | 1170 (60.6) | 762 (39.4) | ||
| Age, years | |||||
| Mean, n (SD) | 71.6 (12.3) | 72.4 (12.3) | 70.47 (12.3) | ||
| Median | 74 | 75 | 73 | ||
| Sex, female (%) | 53.8 | 49.8 | 60.0 | ||
| Persistence (time to discontinuation) | |||||
| 3 months, n (%) | 1457 | 922 (78.8) | 535 (70.2) | <0.001 | −8.6 (−12.6 to −4.6) |
| 6 months, n (%) | 1231 | 804 (68.7) | 427 (56.0) | <0.001 | −12.7 (−17.1 to −8.3) |
| 9 months, n (%) | 1097 | 733 (62.6) | 364 (47.8) | <0.001 | −14.9 (−19.4 to −10.4) |
| 12 months, n (%) | 1015 | 686 (58.6) | 329 (43.2) | <0.001 | −15.5 (−20.0 to −10.9) |
| New patients with treatment | |||||
| 3 months, n (%) | 380 | 228 (19.5) | 152 (19.9) | 0.782 | 0.5 (−3.2 to 4.1) |
| 6 months, n (%) | 552 | 371 (31.7) | 181 (23.8) | <0.001 | −8.0 (−12.0 to −3.9) |
| 9 months, n (%) | 611 | 433 (37.0) | 178 (23.4) | <0.001 | −13.6 (−17.7 to −9.6) |
| 12 months, n (%) | 809 | 595 (50.9) | 214 (28.1) | <0.001 | −22.8 (27.1 to 18.5) |
| Patient characteristics at the end, 12 months,a (%) | |||||
| Patients, n | 1824 | 1281 (70.2) | 543 (29.8%) | ||
| Sex, female (%) | 51.0 | 48.0 | 58.1 | ||
↵a Initial patients with persistence to treatment plus new treatments. CI = confidence interval. SD = standard deviation.