Paracetamol and tramadol (n = 1168) | Amitriptyline (n = 1183) | NSAID (ketoprofen) (n = 1183) | ||||
---|---|---|---|---|---|---|
Variables | AOR (95% CI) | P-value | AOR (95% CI) | P-value | AOR (95% CI) | P-value |
Stratification variables | ||||||
Age (ref <50 years) | ||||||
50–58 years | 0.77 (0.54 to 1.12) | 0.17 | 0.85 (0.57 to 1.26) | 0.41 | 0.91 (0.65 to 1.26) | 0.57 |
>58 years | 0.73 (0.47 to 1.13) | 0.16 | 0.89 (0.56 to 1.43) | 0.64 | 1.65 (1.16 to 2.36) | 0.006 |
Sex (ref Male) | ||||||
Female | 1.13 (0.80 to 1.61) | 0.48 | 1.28 (0.88 to 1.86) | 0.20 | 0.87 (0.64 to 1.18) | 0.37 |
Workload (ref <3067 consultations and visits) | ||||||
3067–6028 | 1.22 (0.79 to 1.89) | 0.36 | 1.42 (0.88 to 2.27) | 0.15 | 1.05 (0.73 to 1.51) | 0.80 |
>6028 | 1.26 (0.77 to 2.06) | 0.36 | 1.21 (0.70 to 2.11) | 0.49 | 0.93 (0.61 to 1.41) | 0.73 |
GP density of the municipality of practice (ref < −19.3% of the national average) | ||||||
−19.3% to +17.7% of the national average | 0.72 (0.50 to 1.04) | 0.08 | 1.14 (0.75 to 1.72) | 0.54 | 0.86 (0.62 to 1.18) | 0.35 |
> +17.7% of the national average | 0.75 (0.48 to 1.17) | 0.20 | 1.28 (0.79 to 2.07) | 0.32 | 1.03 (0.71 to 1.50) | 0.86 |
Professional characteristics | ||||||
Practice of complementary medicine (for example, homeopathy, acupuncture) (ref ‘No’) | ||||||
Yes | 1.62 (1.01 to 2.58) | 0.04 | NR | NR | ||
Reported proportion of patients with multimorbidity on GP’s list (ref <25%) | ||||||
25–50% | 0.98 (0.70 to 1.37) | 0.90 | NR | NR | ||
>50% | 0.51 (0.28 to 0.92) | 0.02 | NR | NR | ||
Patients’ characteristics | ||||||
Age, years (ref 54 years) | ||||||
82 | NR | NR | 0.48 [0.36 to 0.63] | <0.001 | ||
History of stroke (ref ‘No’) | ||||||
Yes | NR | 0.63 [0.45 to 0.90] | 0.01 | 0.55 [0.42 to 0.72] | <0.001 |
AOR = adjusted odds ratio. NR = not retained in the backward selection procedure. NSAID = non-steroidal anti-inflammatory drug. Ref = reference.