Differences in Framingham risk estimates using alternative summary measures of mean blood pressure in the HOMERUS cohort
| Alternative BP measurement used in risk score | Median absolute difference, % (IQR) | Difference range (original minus alternative) |
|---|---|---|
| Ambulatory measurements | ||
| Daytime ABPM | 2.76 (1.19 to 6.39) | −8.65 to 18.80 |
| Night-time ABPM | 5.35 (2.04 to 11.42) | −5.88 to 28.28 |
| 24-hour ABPM | 3.05 (1.10 to 7.40) | −7.97 to 20.93 |
| Home measurements | ||
| Excluding first day’s readings | 2.50 (0.89 to 5.32) | −8.52 to 16.33 |
| Including first day’s readings | 2.41 (0.92 to 5.24) | −9.03 to 16.05 |
| Clinic measurements | ||
| Current UK guidance | 0.51 (0.21 to 1.32) | −3.56 to 4.34 |
ABPM = ambulatory blood pressure monitoring. BP = blood pressure. HOMERUS = Home versus Office blood pressure Measurements: Reduction of Unnecessary treatment Study. IQR = interquartile range.