Characteristics of the BP-Eth and HOMERUS cohorts
| Variable | BP-Eth cohort (N = 442) | HOMERUS cohort (N= 165) |
|---|---|---|
| Demographics | ||
| Age, years, mean (SD) | 58.4 (9.4) | 55.6 (9.7) |
| Females, n (%) | 222 (50.2) | 75 (45.5) |
| BMI, kg/m2, mean (SD) | 29.1 (4.5) | 27.5 (4.2) |
| Current smoker, n (%) | 66 (14.9) | 30 (18.2) |
| Morbidity, n (%) | ||
| Chronic kidney disease | 30 (6.8) | 0 (0.0) |
| Atrial fibrillation | 16 (3.6) | 0 (0.0) |
| Treated hypertension | 249 (56.3) | 165 (100.0) |
| Left ventricular hypertrophy | 0 (0.0) | 0 (0.0) |
| Type 1 diabetes | 2 (0.5) | 6 (3.6) |
| Type 2 diabetes | 57 (12.9) | 37 (22.4) |
| Townsend score | 6.1 (4.1) | 0.1 (0.06) |
| Lipids, mean (SD) | ||
| Total cholesterol, mmol/L | (simulated) 5.4 (1.1) | 5.5 (1.1) |
| HDL cholesterol, mmol/L | (simulated) 1.5 (0.4) | 1.4 (0.4) |
| Total/HDL cholesterol, mmol/L | 4.0 (1.7) | 4.4 (1.4) |
| Ethnicity, n (%) | ||
| White | 203 (45.9) | 165 (100.0) |
| Indian | 79 (17.9) | 0 (0.0) |
| Pakistani | 24 (5.4) | 0 (0.0) |
| Bangladeshi | 5 (1.1) | 0 (0.0) |
| Black Caribbean | 115 (26.0) | 0 (0.0) |
| Black African | 16 (3.6) | 0 (0.0) |
| Systolic blood pressure, mmHg | ||
| Single reading (random arm), mean (SD) | 136.2 (18.3) | 146.5 (19.1) |
| Mean of second and third readings in left arm (SD) | 132.4 (17.1) | 142.3 (17.1) |
| According to current guidance, mean (SD) | 132.8 (15.9) | 141.4 (16.2) |
| Mean of home readings excluding the first day (SD) | 133.4 (12.4) | 134.0 (10.5) |
| Mean of daytime ambulatory readings (SD) | 133.0 (14.2) | 131.3 (9.9) |
| Cardiovascular risk | ||
| QRISK2, 10-year | 16.0 (12.1) | 13.2 (8.8) |
| Framingham, 10-year | 15.6 (10.8) | 19.6 (13.5) |
| SCORE, 10-year (CVD mortality risk) | 3.1 (3.3) | 3.3 (3.7) |
BMI = body mass index. BP-Eth = Blood Pressure in different Ethnic groups study. CVD = cardiovascular disease. HDL = high-density lipoprotein. HOMERUS = Home versus Office blood pressure MEasurements: Reduction of Unnecessary treatment Study. SCORE = systematic coronary risk evaluation. SD = standard deviation.