Table 2.

NNT to prevent one major vascular event in each sample profile

Absolute 5 year risk of fatal and non-fatal CVD events^a, %	RR reduction in major vascular events from taking statins^b (95% CI)	Absolute risk reduction of major vascular events from taking statins, %	NNT, n
Low risk (<1)	0.75 (0.70 to 0.80)	0.25	≥400
Moderate risk (1–7.4)	0.75 (0.70 to 0.80)	0.25–1.9	400–53
High risk (7.5–15.9)	0.75 (0.70 to 0.80)	1.9–4.0	53–25
Very high risk (≥16)	0.75 (0.70 to 0.80)	4.0	≤25

↵a Risk conversions are available from the authors on request.
↵b RR reported for the outcome ‘Major vascular events’ as reported in Cholesterol Treatment Trialists Collaboration.²⁶ NNT = numbers needed to treat. RR = risk ratio.