Author, year | TP | FP | FN | TN | Sensitivity | Specificity | LR+ | LR− | DOR | AUC |
---|---|---|---|---|---|---|---|---|---|---|
CAP (adults) | ||||||||||
Gonzalez-Ortiz, 199530 | 24 | 6 | 29 | 82 | 0.45 | 0.93 | 6.6 | 0.59 | ||
Lieberman, 200331 | 14 | 37 | 5 | 194 | 0.74 | 0.84 | 4.6 | 0.31 | ||
Melbye, 198832 | 3 | 3 | 8 | 57 | 0.27 | 0.95 | 5.5 | 0.77 | ||
Moberg, 201633 | 14 | 2 | 30 | 53 | 0.32 | 0.96 | 8.6 | 0.71 | ||
Tape (Illinois), 199117 | 58 | 108 | 63 | 876 | 0.48 | 0.89 | 4.4 | 0.58 | ||
Tape (Nebraska), 199117 | 24 | 9 | 14 | 72 | 0.63 | 0.89 | 5.7 | 0.41 | ||
Tape (Virginia), 199117 | 24 | 14 | 6 | 96 | 0.80 | 0.87 | 6.3 | 0.23 | ||
van Vugt, 201311 | 41 | 31 | 99 | 2639 | 0.29 | 0.99 | 25.2 | 0.72 | ||
Summary estimate (95% CI) | 0.50 (0.37 to 0.62) | 0.93 (0.87 to 0.97) | 7.7 (4.8 to 11.5) | 0.54 (0.42 to 0.65) | 14.2 (9.0 to 21.0) | 0.80 | ||||
CAP (children) | ||||||||||
Grossman, 198827 | 41 | 33 | 10 | 77 | 0.80 | 0.70 | 2.7 | 0.28 | ||
Mahabee-Gittens, 200528 | 6 | 56 | 38 | 410 | 0.14 | 0.88 | 1.1 | 0.98 | ||
Redd, 199429 | 19 | 20 | 21 | 166 | 0.48 | 0.89 | 4.4 | 0.59 | ||
Summary estimate (95% CI) | 0.46 (0.12 to 0.84) | 0.84 (0.70 to 0.92) | 2.7 (1.1 to 4.3) | 0.63 (0.20 to 0.98) | 5.5 (1.1 to 16) | 0.80 | ||||
ARS (adults)a | ||||||||||
Berg, 198123 | 21 | 2 | 4 | 23 | 0.84 | 0.92 | 10.5 | 0.17 | ||
Berg, 198524 | 33 | 11 | 10 | 36 | 0.77 | 0.77 | 3.3 | 0.30 | ||
Berg, 198825 | 52 | 16 | 27 | 60 | 0.66 | 0.78 | 3.0 | 0.44 | ||
Williams, 199226 | 72 | 55 | 23 | 97 | 0.76 | 0.64 | 2.1 | 0.38 | ||
Summary estimate (95% CI) | 0.73 (0.66 to 0.79) | 0.75 (0.64 to 0.84) | 3.0 (2.1 to 4.4) | 0.37 (0.29 to 0.46) | 8.3 (4.9 to 13.1) | 0.77 | ||||
ABRS (adults)a | ||||||||||
Berg, 198123 | 21 | 2 | 4 | 23 | 0.84 | 0.92 | 10.5 | 0.17 | ||
Berg, 198524 | 33 | 11 | 10 | 36 | 0.77 | 0.77 | 3.3 | 0.30 | ||
Berg, 198825 | 52 | 16 | 27 | 60 | 0.66 | 0.78 | 3.0 | 0.44 | ||
Summary estimate (95% CI) | 0.74 (0.61 to 0.84) | 0.80 (0.72 to 0.87) | 3.9 (2.4 to 5.9) | 0.33 (0.20 to 0.50) | 13.0 (5.0 to 27) | 0.84 | ||||
GABHS pharyngitis (both) | ||||||||||
Attia, 200134 | 157 | 148 | 61 | 221 | 0.72 | 0.60 | 1.8 | 0.47 | ||
Centor, 19818 | 29 | 47 | 11 | 147 | 0.73 | 0.76 | 3.0 | 0.36 | ||
Dobbs, 199622 | 44 | 47 | 28 | 87 | 0.61 | 0.65 | 1.7 | 0.60 | ||
Summary estimate (95% CI) | 0.69 (0.61 to 0.76) | 0.67 (0.57 to 0.76) | 2.1 (1.6 to 2.8) | 0.47 (0.36 to 0.60) | 4.6 (2.6 to 7.8) | 0.73 |
↵a ARS was defined as sinusitis diagnosed using any reference standard, whereas ABRS was defined as sinusitis diagnosed using antral puncture fluid inspection as the reference standard. ABRS = acute bacterial rhinosinusitis. ARS = acute rhinosinusitis. AUC = area under the receiver operating characteristic curve. CAP = community-acquired pneumonia. DOR = diagnostic odds ratio (LR+/LR−). FN = false negative. FP = false positive. GABHS = group A beta-haemolytic streptococcal. LR− = negative likelihood ratio. LR+ = positive likelihood ratio. TN = true negative. TP = true positive.