Table 4.

Cascade effects of testing in 6-month period after testing

Mean number of GP appointments per persona (95% CI)Mean number of phlebotomy appointments in 6 months (95% CI)Mean number of total tests requested (95% CI)Mean number of referrals per person (95% CI)
True-positives, n= 571215.0b (14.7 to 15.3)4.26b (4.15 to 4.37)43.7b (42.3 to 45.2)0.86b (0.83 to 0.89)
False-negatives, n= 591212.0b (11.7 to 12.2)3.23b (3.14 to 3.32)30.0b (28.8 to 31.2)0.78b (0.75 to 0.81)
False-positives, n= 32 29810.3b (10.2 to 10.4)2.78b (2.75 to 2.82)24.3b (23.9 to 24.7)0.62b (0.61 to 0.64)
True-negatives, n= 93 0397.29b (7.2 to 7.3)1.81b (1.80 to 1.83)13.7b (13.5 to 13.8)0.52b (0.51 to 0.52)
Untested controls n= 37 5394.80 (4.74 to 4.86)1.14 (1.12 to 1.16)9.66 (9.47 to 9.85)0.24 (0.24 to 0.25)
  • True-positives = people with a positive test who develop relevant disease. False-negatives = people with a negative test who develop relevant disease. False-positives = people with a positive test with no relevant disease. True-negatives = people with a negative test with no relevant disease.

  • a Includes face-to-face consultations, home visits, and telephone consultations.

  • b P<0.001 — comparing true-positives to false-negatives and comparing false-positives to true-negatives.