Comparison of summary statistics of different covariates (patient characteristics, drug class, number of medications, use of combined medications, morbidity, and ABPM readings) among adherent and non-adherent (partially or fully non-adherent) groups (N = 235)
| Covariate | Non-adherent n (%)a (n= 61) | Adherent n (%)a (n= 174) | P-value |
|---|---|---|---|
| Age, mean (SD) | 69.9 (11.4) | 69.8 (10.4) | 0.956 |
| Sex | 0.923 | ||
| Male | 35 (57.4) | 103 (59.2) | |
| Female | 26 (42.6) | 71 (40.8) | |
| Diabetes | 0.982 | ||
| No | 42 (68.9) | 122 (70.1) | |
| Yes | 19 (31.1) | 52 (29.9) | |
| Chronic kidney disease | 0.429 | ||
| Not CKD | 43 (70.5) | 111 (63.8) | |
| CKD | 18 (29.5) | 63 (36.2) | |
| Angiotensin receptor blocker | 0.214 | ||
| No | 34 (55.7) | 79 (45.4) | |
| Yes | 27 (44.3) | 95 (54.6) | |
| Beta-blocker | 0.297 | ||
| No | 27 (44.3) | 62 (35.6) | |
| Yes | 34 (55.7) | 112 (64.4) | |
| ACE inhibitor | 0.095 | ||
| No | 29 (47.5) | 106 (60.9) | |
| Yes | 32 (52.5) | 68 (39.1) | |
| Calcium channel blocker | 0.306 | ||
| No | 21 (34.4) | 46 (26.4) | |
| Yes | 40 (65.6) | 128 (73.6) | |
| Diuretic | 0.460 | ||
| No | 1 (1.6) | 9 (5.2) | |
| Yes | 60 (98.4) | 165 (94.8) | |
| 3 medications | 1.000 | ||
| >3 medications | 34 (55.7) | 98 (56.3) | |
| 3 medications only | 27 (44.3) | 76 (43.7) | |
| Combination medications | 0.385 | ||
| No | 18 (29.5) | 64 (36.8) | |
| Yes | 43 (70.5) | 110 (63.2) | |
| Documented CCF | 0.791 | ||
| Not documented | 54 (88.5) | 158 (90.8) | |
| Documented | 7 (11.5) | 16 (9.2) | |
| Mean systolic day ABPM, mmHg (SD) | 137 (15.6) | 135 (16.0) | 0.435 |
| Mean diastolic day ABPM, mmHg (SD) | 73.4 (11.2) | 73.1 (9.82) | 0.829 |
| Mean systolic night ABPM, mmHg (SD) | 131 (19.7) | 129 (20.6) | 0.513 |
| Mean diastolic night ABPM, mmHg (SD) | 67.8 (13.7) | 66.7 (11.9) | 0.609 |
| ABPM total systolic, mmHg | 135 (16.5) | 133 (16.8) | 0.441 |
| ABPM total diastolic, mmHg | 71.2 (11.5) | 70.5 (9.80) | 0.708 |
| WCH | 0.136 | ||
| No | 51 (83.6) | 127 (73.0) | |
| Yes | 10 (16.4) | 47 (27.0) | |
↵a Number of participants and percentage, unless specified. ABPM = ambulatory blood pressure monitoring. CCF = congestive cardiac failure. WCH = white-coat hypertension.