Number of patients with each index symptom in the year before diagnosis with lung cancera
| Index symptom | Number of patients diagnosed in 2000, N= 971 (%) | Number of patients diagnosed in 2017, N= 900 (%) | OR per year (95% CI) | P-value | |
|---|---|---|---|---|---|
| Increasing over time | Combination (more than one symptom including cough) | 5 (1) | 22 (2) | 1.08 (1.06 to 1.10) | <0.0001 |
| Dyspnoea | 128 (13) | 197 (22) | 1.05 (1.05 to 1.06) | <0.0001 | |
| Cough | 211 (22) | 207 (23) | 1.01 (1.00 to 1.02) | <0.0001 | |
| Decreasing over time | Fatigue | 38 (4) | 22 (2) | 0.99 (0.97 to 1.00) | 0.0270 |
| Combination (more than one symptom excluding cough) | 6 (1) | 7 (1) | 0.98 (0.96 to 1.01) | 0.3040 | |
| Weight loss | 31 (3) | 17 (2) | 0.98 (0.96 to 0.99) | 0.004 | |
| Chest pain | 108 (11) | 57 (6) | 0.96 (0.95 to 0.97) | <0.0001 | |
| Appetite loss | 9 (1) | 2 (0) | 0.94 (0.90 to 0.97) | <0.0001 | |
| Haemoptysis | 57 (6) | 16 (2) | 0.93 (0.92 to 0.95) | <0.0001 | |
| Total | 593 (61) | 547 (61) | |||
↵a For brevity, data for the intervening annual cohorts 2001–2016 are not shown. The odds ratio reports the change in proportion of patients with each index symptom per year, from 2000–2017. OR = odds ratio.