Summary of one-way sensitivity analyses conducted and optimal strategy based on WTP of £20 000
| Parameter | Change | Optimal strategy |
|---|---|---|
| Cost of RDC | Change number of patients per day from 2.78 to 5 | RDC (outperforms) |
| Cost of RDC | Change number of patients per day from 2.78 to 4 | RDC (outperforms) |
| Cost of RDC | Change number of patients per day from 2.78 to 3 | No RDC (ICER = £22 140) |
| Cost of RDC | Change number of patients per day from 2.78 to 2 | No RDC (ICER = £69 969) |
| Cost of RDC | Change number of patients per day from 2.78 to 1 | No RDC (ICER = £213 459) |
| All costs | Add 20% to all costs | No RDC (ICER = £35 678) |
| All costs | Subtract 20% from all costs | No RDC (ICER = £23 786) |
| All costs | Add 50% to all costs | No RDC (ICER = £44 598) |
| All costs | Subtract 50% from all costs | RDC (ICER = £14 866) |
| Adjusted OR for control group cancer patients | After 2 months increase cancer QALY OR from 0.69 to 0.95 | No RDC (ICER = £34 848) |
| Cancer diagnosis utility | Utility decreases by 3% to 0.602 | No RDC (ICER = £62 637) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis | No RDC (ICER = £245 102) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 5 per day | RDC (outperforms) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 4 per day | RDC (outperforms) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 3 per day | No RDC (£182 514) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 2 per day | No RDC (ICER = £576 811) |
| Utility | Keep all utilities 0.664 rather than 0.62 for all patients until diagnosis with number of patients 1 per day | No RDC (ICER = £1 759 700) |
ICER = incremental cost-effectiveness ratio. OR = odds ratio. QALY = quality-adjusted life year. RDC = rapid diagnosis centre. WTP = willingness-to-pay.