Table 2.

Sensitivity and specificity of the Centor and McIsaac scores at different thresholds

ThresholdSensitivity, % (95% CI)Specificity, % (95% CI)LR+ (95% CI)LR− (95% CI)
Centor score
197.2 (96.4 to 97.8)10.1 (6.3 to 15.2)1.08 (1.05 to 1.14)0.28 (0.23 to 0.45)
284.4 (81.4 to 87.0)36.7 (28.8 to 45.1)1.33 (1.19 to 1.50)0.43 (0.39 to 0.55)
354.4 (48.7 to 60.0)72.4 (64.4 to 79.4)1.97 (1.46 to 2.40)0.63 (0.58 to 0.74)
421.5 (16.6 to 27.2)93.7 (89.6 to 96.4)3.41 (1.83 to 4.97)0.84 (0.78 to 0.90)
McIsaac score
099.7 (99.0 to 99.9)2.3 (0.3 to 10.7)1.02 (1.00 to 1.10)0.15 (0.09 to 0.35)
197.5 (94.7 to 99.0)10.8 (2.8 to 28.4)1.09 (1.02 to 1.30)0.23 (0.17 to 0.39)
288.0 (82.0 to 93.8)31.5 (14.2 to 54.3)1.30 (1.09 to 1.76)0.35 (0.28 to 0.47)
368.7 (57.4 to 78.5)60.8 (39.9 to 78.8)1.75 (1.28 to 2.79)0.51 (0.44 to 0.58)
440.0 (28.5 to 52.5)84.8 (70.8 to 93.4)2.64 (1.68 to 4.95)0.71 (0.62 to 0.78)
516.1 (8.9 to 26.2)96.3 (90.8 to 98.7)4.32 (2.38 to 10.0)0.87 (0.79 to 0.93)
  • CI = confidence interval. LR+ = positive likelihood ratio. LR− = negative likelihood ratio.