Table 1.

Regression models predicting 1-year incidence of all cancers, lung cancer, and colorectal cancera

CovariateAll cancers, ORb (95% CI)P-valueLung cancer, ORb (95% CI)P-valueColorectal cancer, ORb (95% CI)P-value
Age, years
40–49 (reference)1.001.001.00
50–591.72 (1.54 to 1.93)<0.0013.94 (1.97 to 7.89)<0.0012.61 (1.88 to 3.61)<0.001
60–692.88 (2.60 to 3.20)<0.0019.11 (4.74 to 17.49)<0.0015.36 (3.96 to 7.26)<0.001
70–794.30 (3.88 to 4.76)<0.00110.5 (5.44 to 20.26)<0.0019.74 (7.26 to 13.08)<0.001
≥804.30 (3.86 to 4.79)<0.0017.55 (3.74 to 15.23)<0.0019.44 (6.94 to 12.84)<0.001
Sex
Female (reference)1.001.001.00
Male2.01 (1.90 to 2.13)<0.0011.63 (1.26 to 2.09)<0.0012.01 (1.77 to 2.29)<0.001
Smoking status
Non-smoker (reference)1.001.001.00
Past/current smoker1.01 (0.94 to 1.07)0.8683.71 (2.41 to 5.70)<0.0010.88 (0.77 to 1.01)0.079
Platelet count (× 109/l)
150–325 (reference)1.001.001.00
326–3501.36 (1.26 to 1.47)<0.0013.84 (2.38 to 6.19)<0.0012.60 (2.10 to 3.22)<0.001
351–3751.56 (1.44 to 1.70)<0.0014.49 (2.73 to 7.37)<0.0013.76 (3.02 to 4.68)<0.001
376–4001.63 (1.49 to 1.79)<0.0014.68 (2.79 to 7.87)<0.0013.93 (3.12 to 4.97)<0.001
• a Each model used data from all 295 312 patients.

• b ORs of >1 indicate increased odds of cancer relative to the reference group; ORs of <1 indicate decreased odds. CI = confidence interval. OR = odds ratio.