Table 1.

Regression models predicting 1-year incidence of all cancers, lung cancer, and colorectal cancer^a

Covariate	All cancers, OR^b (95% CI)	P-value	Lung cancer, OR^b (95% CI)	P-value	Colorectal cancer, OR^b (95% CI)	P-value
Age, years
40–49 (reference)	1.00	—	1.00	—	1.00	—
50–59	1.72 (1.54 to 1.93)	<0.001	3.94 (1.97 to 7.89)	<0.001	2.61 (1.88 to 3.61)	<0.001
60–69	2.88 (2.60 to 3.20)	<0.001	9.11 (4.74 to 17.49)	<0.001	5.36 (3.96 to 7.26)	<0.001
70–79	4.30 (3.88 to 4.76)	<0.001	10.5 (5.44 to 20.26)	<0.001	9.74 (7.26 to 13.08)	<0.001
≥80	4.30 (3.86 to 4.79)	<0.001	7.55 (3.74 to 15.23)	<0.001	9.44 (6.94 to 12.84)	<0.001

Sex
Female (reference)	1.00	—	1.00	—	1.00	—
Male	2.01 (1.90 to 2.13)	<0.001	1.63 (1.26 to 2.09)	<0.001	2.01 (1.77 to 2.29)	<0.001

Smoking status
Non-smoker (reference)	1.00	—	1.00	—	1.00	—
Past/current smoker	1.01 (0.94 to 1.07)	0.868	3.71 (2.41 to 5.70)	<0.001	0.88 (0.77 to 1.01)	0.079

Platelet count (× 10⁹/l)
150–325 (reference)	1.00	—	1.00	—	1.00	—
326–350	1.36 (1.26 to 1.47)	<0.001	3.84 (2.38 to 6.19)	<0.001	2.60 (2.10 to 3.22)	<0.001
351–375	1.56 (1.44 to 1.70)	<0.001	4.49 (2.73 to 7.37)	<0.001	3.76 (3.02 to 4.68)	<0.001
376–400	1.63 (1.49 to 1.79)	<0.001	4.68 (2.79 to 7.87)	<0.001	3.93 (3.12 to 4.97)	<0.001

↵a Each model used data from all 295 312 patients.
↵b ORs of >1 indicate increased odds of cancer relative to the reference group; ORs of <1 indicate decreased odds. CI = confidence interval. OR = odds ratio.