Multivariable adjusted odds ratios for all-cause mortality in the RCGP RSC cohort with known SARS-COV-2 status
| Variable/category | OR | 95% CI | P-value |
|---|---|---|---|
| SARS-COV-2 status (ref: negative test) | |||
| Possible | 1.5401 | 1.1649 to 2.0362 | 0.0024 |
| Probable | 9.6763 | 7.1185 to 13.1533 | <0.0001 |
| Definite | 8.9032 | 6.6730 to 11.8788 | <0.0001 |
| URTI (ref: no URTI) | 0.5522 | 0.2781 to 1.0963 | 0.0896 |
| LRTI (ref: no LRTI) | 1.2389 | 0.8367 to 1.8345 | 0.2847 |
| Age band, years (ref: <65) | |||
| 65–74 | 7.9265 | 6.4285 to 9.7735 | <0.0001 |
| ≥75 | 18.7132 | 15.1709 to 23.0826 | <0.0001 |
| Male sex (ref: female) | 1.7665 | 1.3735 to 2.0340 | <0.0001 |
| Household size (ref: single occupancy) | |||
| 2–4 people | 0.8151 | 0.6958 to 0.9549 | 0.0114 |
| 5–8 people | 1.1629 | 0.9027 to 1.4983 | 0.2429 |
| ≥9 | 2.8045 | 2.2784 to 3.4522 | <0.0001 |
| Population density (ref: city and town) | |||
| Conurbation | 1.2887 | 1.0991 to 1.5109 | 0.0018 |
| Rural | 0.9207 | 0.7577 to 1.1187 | 0.4058 |
| Deprivation IMD quintile (ref: 1 — most deprived) | |||
| 2 | 0.9872 | 0.8082 to 1.2058 | 0.8992 |
| 3 | 0.9234 | 0.7364 to 1.1579 | 0.4900 |
| 4 | 0.9246 | 0.7501 to 1.1398 | 0.4628 |
| 5 (least deprived) | 1.0516 | 0.8435 to 1.3111 | 0.6545 |
| Ethnicity (ref: white) | |||
| Asian | 1.2842 | 0.9613 to 1.7154 | 0.0904 |
| Black | 1.8424 | 1.3342 to 2.5440 | 0.0002 |
| Mixed, Other | 1.3162 | 0.8616 to 2.0105 | 0.2037 |
| BMI band (ref: normal weight) | |||
| Overweight | 0.7966 | 0.6819 to 0.9306 | 0.0041 |
| Obese | 0.8547 | 0.7073 to 1.0328 | 0.1039 |
| Severely obese | 1.5323 | 1.0061 to 2.3335 | 0.0468 |
| Smoking status (ref: non-smoker) | |||
| Active | 0.7925 | 0.5416 to 1.0894 | 0.0910 |
| Ex-smoker | 0.5700 | 0.4512 to 0.7202 | 0.0001 |
| Long-term conditions: (ref: absence of condition) | |||
| Type 1 diabetes | 0.9607 | 0.2856 to 3.2313 | 0.9483 |
| Type 2 diabetes | 1.1982 | 0.9968 to 1.4403 | 0.0542 |
| Hypertension | 1.0897 | 0.9383 to 1.2654 | 0.2603 |
| Chronic kidney disease | 1.4131 | 1.1618 to 1.7187 | 0.0005 |
| Chronic heart disease | 1.1814 | 1.0046 to 1.3893 | 0.0438 |
| Chronic respiratory | 1.2986 | 1.0173 to 1.6575 | 0.0359 |
| Cancer or immunocompromised | 1.2972 | 1.0776 to 1.5616 | 0.0060 |
| Learning disability | 1.9682 | 1.2186 to 3.1788 | 0.0056 |
BMI = body mass index. CI = confidence interval. IMD = index of multiple deprivation. LRTI = lower respiratory infections. OR = odds ratio. ref = reference category. RCGP RSC = Oxford Royal College of General Practitioners Research and Surveillance Centre network. URTI = upper respiratory infections.