Table 1.

Baseline characteristics

	Study 1²¹	Study 2¹²	Total sample
N, total participants	772	1269	2041

Observations, n
Weight	4033	3952	7985
BP	3853	3939	7792
HbA1c	1265	1314	2579
Blood test, other (glucose, lipid profile – n)	2251	1329	3580

Sex, n
Male	104	408	512
Female	668	861	1529

Ethnicity, n
White	482	1138	1620
Asian	23	26	49
Black	4	22	26
Other	68	41	109

Data not available	195	42	237

Age (years)^a	47 (12.7)	53 (13.7)	50 (13.5)

Baseline BMI (kg/m²)^a	31.4 (2.6)	34.5 (5.1)	32.7 (4.1)

Baseline Weight (kg)^a	86.7 (11.5)	96.1 (17)	90.6 (14.8)

Baseline HbA1c (mmol/mol)^a	38.2 (5.3)	41.3 (10.2)	39.2 (7.4)

Baseline Glucose (mmol/L)^a	5.0 (0.8)	5.7 (1.7)	5.2 (1.2)

Baseline SBP (mmHg)^a	124 (16)	133 (17)	128 (17)

Baseline DBP (mmHg)^a	79 (9)	80 (10)	79 (10)

Baseline Total cholesterol (mmol/L)^a	5.3 (1)	5.3 (1.1)	5.3 (1)

Baseline HDL cholesterol (mmol/L)^a	1.4 (0.4)	1.7 (0.6)	1.5 (0.5)

Baseline LDL cholesterol (mmol/L)^a	3.2 (0.9)	3.0 (1.0)	3.1 (0.9)

Baseline Triglycerides (mmol/L)^a	1.5 (0.9)	1.5 (0.8)	1.5 (0.9)

Diabetes at baseline, n (%)	51 (6.6)	190 (14.9)	241 (11.8)

Hypertension at baseline, n (%)	92 (11.9)	631 (49.7)	723 (35.4)

↵a mean (standard deviation). BMI = body mass index. BP = blood pressure. DBP = diastolic blood pressure. HbA1c = glycated haemoglobin. HDL = high-density lipoprotein. LDL = low-density lipoprotein. SBP = systolic blood pressure.