Box 1.

Interview topic guide

Experiences and opinions
  • Can you think of a patient for whom discontinuing long-term antidepressant use was successful and describe the experience and the process used? (long-term >2 years)

  • Now can you think of a patient for whom discontinuing long-term antidepressant use was unsuccessful and describe how the experience was different and why you think the attempt was unsuccessful?

  • We know distinguishing between relapse and withdrawal symptoms can be challenging, can you talk a little about your experience with this in relation to discontinuing long-term antidepressant use?

  • Can you describe your monitoring and reviewing process for patients on antidepressant therapy?

  • In general terms, what do you think about the role of antidepressants in treating depression?

Decision-making
  • What factors play a role in your decision to continue or discontinue long-term antidepressant use?

  • What do you see as the risks of stopping long-term antidepressant treatment?

  • What do you see as the benefits of stopping long-term antidepressant treatment?

Support for GPs
  • To what extent do you feel you have sufficient knowledge and experience to advise patients correctly and to help them with discontinuing antidepressants?

  • What would you need to discontinue long-term antidepressant use with more patients?

Non-pharmacological support for patients
  • What non-pharmacological interventions do you refer patients to?

  • Are you aware of any low-intensity non-pharmacological interventions (such as online CBT, guided self-help, wellbeing apps or websites) for patients and do you ever suggest them to your patients?

  • The idea of social prescribing in general practice (or community referral to social groups) is gaining momentum as a model of care, do you have any thoughts about it and its use in supporting patients who are discontinuing long-term antidepressant use?