Box 1.

Andermann and colleagues’ updated screening criteria for the genomic age3

  • The screening programme should respond to a recognised need.

  • The objectives of screening should be defined at the outset.

  • There should be a defined target population.

  • There should be scientific evidence of screening programme effectiveness.

  • The programme should integrate education, testing, clinical services, and programme management.

  • There should be quality assurance, with mechanisms to minimise potential risks of screening.

  • The programme should ensure informed choice, confidentiality, and respect for autonomy.

  • The programme should promote equity and access to screening for the entire target population.

  • Programme evaluation should be planned from the outset.

  • The overall benefits of screening should outweigh the harm.