Associations with change in treatment burden global score
| Characteristic | Univariable | Multivariablea | ||||
|---|---|---|---|---|---|---|
| βb | 95% CI | P-valuec | βb | 95% CI | P-valuec | |
| Age category, years (versus 55–64) | ||||||
| 65–74 | 0.197 | –4.13 to 4.52 | 0.93 | –1.08 | –5.35 to 3.19 | 0.620 |
| 75–84 | 2.461 | –1.92 to 6.84 | 0.27 | 1.70 | –2.65 to 6.05 | 0.445 |
| ≥85 | 4.27 | –1.11 to 9.66 | 0.12 | 3.17 | –2.33 to 8.68 | 0.258 |
| Sex, female (versus male) | –0.61 | –3.14 to 1.91 | 0.64 | –0.29 | –2.87 to 2.29 | 0.825 |
| Marital status (versus married) | ||||||
| Single | –2.32 | –9.00 to 4.36 | 0.44 | –2.30 | –8.75 to 4.14 | 0.484 |
| Divorced or dissolved partnership | 1.67 | –2.53 to 5.86 | 0.50 | 2.07 | –2.07 to 6.22 | 0.327 |
| Widowed | 0.12 | –2.97 to 3.21 | 0.94 | –1.87 | –5.22 to 1.48 | 0.273 |
| Lives alone (versus with others) | –0.93 | –3.66 to 1.80 | 0.50 | — | — | — |
| Non-homeowner (versus homeowner) | –2.16 | –5.57 to 1.26 | 0.22 | — | — | — |
| Employment status (versus employed) | ||||||
| Unemployed | –2.29 | –12.15 to 7.56 | 0.65 | — | — | — |
| Retired | 2.06 | –2.58 to 6.69 | 0.39 | — | — | — |
| Other | –0.48 | –10.35 to 9.40 | 0.92 | — | — | — |
| Smoking status (versus never smoked) | ||||||
| Ex-smoker | 0.94 | –1.61 to 3.49 | 0.47 | — | — | — |
| Current smoker | –4.35 | –10.64 to 1.94 | 0.18 | — | — | — |
| >5 long-term conditions (versus ≤5) | 5.89 | 1.98 to 9.80 | 0.003 | 8.26 | 4.20 to 12.32 | <0.001 |
| ≥7 medications prescribed (versus <7) | 2.48 | –0.03 to 4.98 | 0.05 | — | — | — |
| Limited health literacy (versus not limited) | 0.46 | –3.40 to 4.31 | 0.82 | — | — | — |
| Some financial difficulty (versus none) | –0.22 | –5.68 to 5.23 | 0.94 | — | — | — |
| ≥1 hour to hospital (versus>1 hour) | 1.22 | –4.61 to 7.04 | 0.68 | — | — | — |
| >10 minutes travel time to GP (versus≤10 minutes) | 3.89 | 1.27 to 6.52 | 0.004 | 3.88 | 1.32 to 6.43 | 0.003 |
| ≥3 out-patient appointments past 6 months (versus <3) | –2.55 | –5.90 to 0.79 | 0.13 | — | — | — |
| ≥3 GP appointments in past 6 months (versus <3) | –1.44 | –3.99 to 1.10 | 0.27 | — | — | — |
| Baseline MTBQ category (versus no burden) | ||||||
| Low | –0.82 | –4.11 to 2.46 | 0.62 | –0.67 | –3.91 to 2.56 | 0.68 |
| Medium | –0.43 | –3.75 to 2.88 | 0.80 | –1.34 | –4.62 to 1.92 | 0.42 |
| High | –4.85 | –8.80 to −0.91 | 0.016 | –7.00 | –11.04 to −2.96 | 0.001 |
↵a Adjusting for age, sex, marital status, travel time to GP, number of long-term conditions, and baseline treatment burden category.
↵b β is the effect of one unit change in predictor on a one unit increase in global score change.
↵c Results in bold are significant at the P < 0.05 level. MTBQ = Multimorbidity Treatment Burden Questionnaire.