Relative prevalence, average systolic BP, and prevalence of cardiometabolic comorbidity in hospital patients aged 40–75 years, per phenotype
| Measure | Phenotype | |||
|---|---|---|---|---|
| Dipper | Non-dipper | Reverse dipper | Extreme reverse dippera | |
| Whole cohort, n= 21 716 | ||||
| Proportion in each phenotype, n (%) | 2290 (10.5) | 8816 (40.6) | 10 610 (48.9) | 2590 (11.9) |
| Daytime systolic BP, mmHg | 130.6 | 126.2 | 124.1 | 122.1 |
| Night-time systolic BP, mmHg | 114.1 | 121.5 | 132.1 | 139.4 |
| Day–night difference, mmHg | −16.5 | −4.7 | +8.0 | +17.3 |
| 24-hour mean systolic BP, mmHg | 124.8 | 125.0 | 127.7 | 129.2 |
| Prevalence of cardiometabolic comorbidity, n (%) | 434 (19.0) | 1805 (20.5) | 3050 (28.7) | 876 (33.8) |
| Males, n= 11 096 | ||||
| Proportion in each phenotype, n (%) | 1050 (9.5) | 4486 (40.4) | 5560 (50.1) | 1332 (12.0) |
| Daytime systolic BP, mmHg | 132.5 | 127.6 | 124.7 | 122.1 |
| Night-time systolic BP, mmHg | 115.9 | 123.1 | 132.8 | 139.6 |
| Day–night difference, mmHg | −16.6 | −4.5 | +8.1 | +17.5 |
| 24-hour mean systolic BP, mmHg | 126.6 | 126.6 | 128.4 | 129.3 |
| Prevalence of cardiometabolic comorbidity, n (%) | 254 (24.2) | 1091 (24.3) | 1918 (34.5) | 534 (40.1) |
| Females, n= 10 720 | ||||
| Proportion in each phenotype, % | 1240 (11.6) | 4430 (41.3) | 5050 (47.1) | 1258 (11.7) |
| Daytime systolic BP, mmHg | 129.0 | 124.6 | 123.5 | 122.0 |
| Night-time systolic BP, mmHg | 112.6 | 119.8 | 131.2 | 139.3 |
| Day–night difference, mmHg | −16.4 | −4.8 | +7.7 | +17.3 |
| 24-hour mean systolic BP, mmHg | 123.2 | 123.4 | 127.0 | 129.1 |
| Prevalence of cardiometabolic comorbidity, n (%) | 180 (14.5) | 714 (16.1) | 1132 (22.4) | 342 (27.2) |
↵a Extreme reverse dippers are a sub-set of the reverse-dipper phenotype. BP = blood pressure.