Characteristic | No HF (n = 208 478) | HF (n = 21 102) |
---|---|---|
Age, years, median (IQR) | 61.0 (52.0–69.0) | 67.0 (60.0–74.0) |
Sex, female, n (%) | 121 668 (58.4) | 10 334 (49.0) |
Ethnicity, n (%) | ||
White | 189 916 (91.1) | 20 025 (94.9) |
Indian | 3318 (1.59) | 195 (0.92) |
Pakistani | 1709 (0.82) | 100 (0.47) |
Bangladeshi | 441 (0.21) | 13 (0.06) |
Chinese | 362 (0.17) | 25 (0.12) |
Other Asian | 1689 (0.81) | 97 (0.46) |
Black Caribbean | 2075 (1.00) | 136 (0.64) |
Black African | 1552 (0.74) | 53 (0.25) |
Other Black | 814 (0.39) | 40 (0.19) |
Mixed | 822 (0.39) | 47 (0.22) |
Other | 1904 (0.91) | 117 (0.55) |
Missing | 3876 (1.86) | 254 (1.20) |
BMI, kg/m2, median (IQR) | 28.7 (25.1–32.9) | 27.7 (24.2–32) |
Smoking status, n (%) | ||
Never | 69 650 (33.4) | 6282 (29.8) |
Former | 105 967 (50.8) | 11 554 (54.8) |
Current | 32 468 (15.6) | 3208 (15.2) |
Missing | 393 (0.19) | 58 (0.27) |
IMD, quintile, n (%) | ||
Q1 (least deprived) | 46 504 (22.3) | 4677 (22.2) |
Q2 | 44 914 (21.5) | 4769 (22.6) |
Q3 | 42 872 (20.6) | 4386 (20.8) |
Q4 | 40 551 (19.5) | 4010 (19.0) |
Q5 (most deprived) | 33 546 (16.1) | 3241 (15.4) |
Missing | 91 (0.04) | 19 (0.09) |
Medical history, n (%)a | ||
Diabetes | 50 856 (24.4) | 5926 (28.1) |
Hypertension | 121 447 (58.3) | 14 341 (68.0) |
Atrial fibrillation | 20 143 (9.7) | 6082 (28.8) |
Angina | 18 258 (8.76) | 2832 (13.42) |
Ischaemic heart disease | 22 949 (11.0) | 3763 (17.8) |
Myocardial infarction | 11 989 (5.75) | 2485 (11.78) |
Stroke | 15 695 (7.53) | 2612 (12.38) |
Valvular disease | 7233 (3.47) | 1405 (6.66) |
Other CVD | 27 588 (13.2) | 4436 (21.0) |
SBP, mmHg, median (IQR) | 136 (126–145) | 135 (124–145) |
DBP, mmHg, median (IQR) | 78 (70–83) | 76 (70–82) |
Total cholesterol, mmol/L, median (IQR) | 4.8 (4.1–5.6) | 4.5 (3.7–5.3) |
BNP, pg/ml, median (IQR) | 54.0 (24.2–125.4) | 335.9 (163.0–845.0) |
NT-proBNP, pg/ml, median (IQR) | 124.0 (56.0–306.0) | 1358.0 (534.0–3230.0) |
Time between NP test and HF diagnosis | ||
Days, median (IQR) | — | 26 (7–65) |
<6 weeks, n (%) | 13 005 (61.6) | |
≥6 weeks,n (%) | — | 8097 (38.4) |
BMI = body mass index; BNP = B-type NP. CVD = cardiovascular disease. DBP = Diastolic blood pressure. HF = heart failure. IMD = Index of multiple deprivation; IQR = interquartile range (25th and 75th percentiles). NP = natriuretic peptide. Q = quintile. SBP = systolic blood pressure.
↵a Percentages do not total 100 due to multimorbidity.