Age (years) at which modelled 9-month cancer risk (%) exceeded 2%, 3%, and 6% in patients with fatigue without co-occurring alarm symptoms/anaemia, by presence of each co-occurring vague symptoma
| Characteristic | Males, age in years | Females, age in years | ||||
|---|---|---|---|---|---|---|
| Risk >2% | Risk >3% | Risk >6% | Risk >2% | Risk >3% | Risk >6% | |
| Patients with fatigue, without alarm symptoms or anaemia | ||||||
| With vague symptoms | 63 | 70 | — | 75 | — | — |
| Without vague symptoms | 67 | 78 | — | — | — | — |
| Pairwise combinations of fatigue with each vague symptom | ||||||
| Abdominal bloating | 65 | 72 | — | 64 | 80 | — |
| Abdominal pain | 60 | 65 | 90 | 64 | 79 | — |
| Back pain | 67 | 80 | — | — | — | — |
| Chest pain | 64 | 70 | — | 77 | — | — |
| Constipation | 62 | 67 | — | 68 | — | — |
| Cough | 66 | 75 | — | — | — | — |
| Diarrhoea | 63 | 69 | — | — | — | — |
| Other upper GI symptoms | 61 | 67 | — | 68 | — | — |
| Dyspnoea | 65 | 72 | — | 71 | — | — |
| Headache | 66 | 74 | — | — | — | — |
| Lower RTI | 65 | 72 | — | — | — | — |
| Other musculoskeletal pain | 67 | 79 | — | — | — | — |
| Testicular pain | 64 | 71 | — | — | — | — |
| Thromboembolic disease | 71 | 95 | — | 99 | — | — |
| Upper RTI | 66 | 75 | — | — | — | — |
| Urinary tract infections | 66 | 77 | — | — | — | — |
| Weight loss | 55 | 59 | 67 | 59 | 65 | — |
↵a Urinary tract infections also include cystitis, dysuria, urgency, painful urination, urine smell. Other upper GI symptom includes dyspepsia, nausea, vomiting, haematemesis, loss of appetite. GI = gastrointestinal. RTI = respiratory tract infections.