Box 1. Testing purpose and filtering questions
Testing purposeFiltering question
Screen for secondary conditions
  •  Are people with the long-term condition at an increased risk of developing the secondary condition that the test is able to detect?

  •  Is there anything the clinician can do to manage or treat this?

  •  Are there clear benefits of earlier detection or treatment?

Detect adverse treatment effects
  •  Are people using these medications at an increased risk of developing the side effect that the test is able to detect?

  •  Is there anything the clinician can do to manage or treat this?

  •  Are there clear benefits of earlier detection or treatment?