Neuron
Volume 69, Issue 4, 24 February 2011, Pages 591-594
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The Doctor's Dilemma: Opiate Analgesics and Chronic Pain

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Opiates are utilized routinely and effectively as a short-term analgesic treatment for a variety of acute pain conditions such as occur following trauma, and for patients with painful terminal diseases such as cancer. Because opiate analgesics are highly addictive substances, their use in the treatment of chronic nonmalignant pain remains controversial.

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