Abstract
In a prevalence study, we evaluated whether recurrent physician-attended URTI episodes are more common in asthmatic children as compared to age- and gender-matched controls. URTI proneness, defined as ≥5 episodes of rhinitis/pharyngitis, sinusitis, laryngitis/tracheitis or otitis media in a 24-month period, was more common in asthmatics than controls (adjusted odds ratio 2.5, 95% confidence interval: 1.1–6.1). As a consequence, antibiotic prescriptions and referrals to hospitals occurred more frequently among asthmatics than controls.
References
Anderson HR, Butland BK, Strachan DP. Trends in prevalence and severity of asthma. Br Med J 1994; 308: 1600–1604.
Dirksen WJ. NHG-Standaard Astma bij kinderen. Dutch College of General Practitioners' guideline Asthma in Children. Huisarts Wet 1998; 41: 130–143.
Koopman LP, Smit HA, Heijnen MA, et al. Respiratory infections in infants: Interaction of parental allergy, child care, and siblings. The PIAMA Study. Pediatrics 2001; 108: 943–948.
Corne JM, Marshall C, Smith S, Schreiber J, Sanderson G, Holgate ST. Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: A longitudinal cohort study. Lancet 2002; 359: 831–834.
Johnston SL, Pattemore PK, Sanderson G, et al. Community study of the role of viral infections in exacerbations of asthma. Br Med J 1995; 310: 1225–1228.
Openshaw PJ, Lemanske RF. Respiratory viruses and asthma: Can the effects be prevented? Eur Respir J Suppl 1998; 27: 35–39.
Heikinen T, Thint M, Chonmaitree T. Prevalence of various respiratory viruses in the middle ear during acute otitis media. N Engl J Med 1999; 340: 260–264.
Rachelefsky GS. National guidelines needed to manage rhinitis and prevent complications. Ann Allergy Asthma Immunol 1999; 82: 296–305.
Hak E, Essen GA van, Stalman WAB, Kuyvenhoven MM, Melker RA de. Is immunizing all patients with chronic lung disease against influenza in the community cost-effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, the Netherlands. J Epidemiol Commun Health 1998; 52: 120–125.
Von Mutius E, Illi S, Hirsch T, Leupold W, Keil U, Weiland SK. Frequency of infections and risk of asthma, atopy and airway hyper-responsiveness in children. Eur Respir J 1999; 14: 4–11.
Smits AJ, Hak E, Stalman WAB, Van Essen GA, Hoes AW, Verheij TJM. Clinical effectiveness of conventional influenza vaccination in asthmatic children. Epidemiol Infect 2002; 128: 205–211.
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Hak, E., Rovers, M.M., Sachs, A.P. et al. Is asthma in 2–12 year-old children associated with physician-attended recurrent upper respiratory tract infections?. Eur J Epidemiol 18, 899–902 (2003). https://doi.org/10.1023/A:1025674816487
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DOI: https://doi.org/10.1023/A:1025674816487