Chest
Clinical Investigations: COPDEvaluation of the Short-Form 36-Item Questionnaire to Measure Health-Related Quality of Life in Patients With COPD
Section snippets
Study Population
A group of 50 male patients with COPD, as defined by the American Thoracic Society,15 with no significant comorbidity were recruited from the outpatient clinic at Dartmouth-Hitch-cock Medical Center. Inclusion criteria were as follows: diagnosis of symptomatic COPD; FEV1/FVC ratio less than 70%; and dyspnea on exertion. Exclusion criteria included the following: cancer; uncontrolled diabetes, hypertension, or psychiatric illness; exertional chest pain; musculoskeletal or neurologic disease with
Results
Between January and December 1992, 50 patients were recruited into the study. Age was 72 ± 8 years (range, 44 to 84 years), height was 173 ± 6 cm (range, 160 to 185 cm), and weight was 75.6 ± 12.9 kg (range, 52 to 107 kg).
Values for the nine components of the SF-36, dyspnea ratings, and physiologic function tests for the group are listed in Table 1. Based on the FEV1 percent of predicted, 9 patients (18%) had mild disease (>65%), 10 patients (20%) had moderate disease (50 to 64%), and 31
Discussion
In 1992, Ware and Sherbourne14 described the conceptual framework and item selection for the SF-36 as part of the Medical Outcomes Study (MOS). Based on experience with the 20-item MOS short-form survey initially reported by Stewart and colleagues12 in 1988, the investigators developed the SF-36 to expand the number of health domains (from six to nine) and to improve the precision of the scales compared with the MOS-20.14 According to Ware and Sherbourne,14 “the comprehensiveness of SF-36 was
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Supported by a grant from Glaxo Research Institute.
revision accepted September 27.