Chest
Original Research: CoughCauses and Clinical Features of Subacute Cough
Section snippets
Patient Selection
In this study, we defined subacute cough as cough lasting 3 to 8 weeks, and chronic cough as cough lasting > 8 weeks. From April 2001 to August 2003, patients with a chief complaint of subacute cough were enrolled in the study. The following were exclusion criteria: (1) current or past dyspnea; (2) wheezing or rales on physical examination; (3) decreased lung function (FEV1 of < 70% predicted; (4) abnormal findings on plain chest radiograph; (5) current smoking; and (6) use of an
Patient Characteristics
Two hundred forty-three patients visited our clinic due to subacute cough during the study period. Among those patients, 184 patients fulfilled the inclusion criteria. The mean (± SD) age was 47.5 ± 14.4 years (age range, 17 to 76 years). The ratio of men to women was 77:107. The mean basal FEV1 was 100.6 ± 13.% predicted, and the mean FEV1/FVC ratio was 85.8 ± 7.4%.
Frequency of the Causes of Subacute Cough
Eighty-nine of 184 patients (48.4%) had postinfectious cough, 61 of 184 patients (33.2%) had PND, and 29 of 184 patients (15.8%)
Discussion
We analyzed prospectively the causes of subacute cough, and our algorithmic approach with initial use of an antihistamine-decongestant was effective. During the study period, 529 patients complained of subacute cough and chronic cough; 184 patients (34.8%) were regarded as having subacute cough. In patients with subacute cough, 62 improved without medication at the second visit, and the cough was not aggravated again during the study period. The percentage of self-limited cough was higher in
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