Treatment of hypertension with ascorbic acid

Lancet. 1999 Dec 11;354(9195):2048-9. doi: 10.1016/s0140-6736(99)04410-4.

Abstract

In a randomised, double-blind, placebo-controlled study we showed that treatment of hypertensive patients with ascorbic acid lowers blood pressure. Further studies of ascorbic acid to treat hypertension, with clinical endpoints, are warranted.

Publication types

  • Clinical Trial
  • Letter
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Ascorbic Acid / administration & dosage*
  • Ascorbic Acid / adverse effects
  • Blood Pressure / drug effects
  • Double-Blind Method
  • Female
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / etiology
  • Male
  • Middle Aged
  • Reactive Oxygen Species / metabolism
  • Treatment Outcome

Substances

  • Reactive Oxygen Species
  • Ascorbic Acid