Hypovitaminosis D: a widespread epidemic

Geriatrics. 2008 Apr;63(4):24-30.

Abstract

Vitamin D insufficiency is widespread, regardless of geographical location. It is particularly prevalent in the elderly and has far-ranging health consequences including: osteoporosis, falls, increased risk of cancer, and altered glucose and lipid metabolism. Increasing evidence strongly supports the benefits of vitamin D supplementation and also reveals that present recommendations are inadequate, especially for older individuals. Although additional studies are still needed to further optimize diagnostic and therapeutic approaches, physicians should consider prescribing cholecalciferol--at least 2000 international units (IU) per day--to all elderly patients. Oral cholecalciferol supplementation at that level is inexpensive, safe, and effective, and has great potential to improve the quality of life of the elderly.

MeSH terms

  • Accidental Falls / prevention & control
  • Aged
  • Cholecalciferol / therapeutic use*
  • Fractures, Bone / etiology
  • Fractures, Bone / prevention & control
  • Humans
  • Inflammation / etiology
  • Inflammation / prevention & control
  • Metabolic Syndrome / etiology
  • Metabolic Syndrome / prevention & control
  • Neoplasms / etiology
  • Neoplasms / prevention & control
  • Osteoporosis / etiology
  • Osteoporosis / prevention & control
  • Ultraviolet Rays
  • Vitamin D / analogs & derivatives
  • Vitamin D / biosynthesis
  • Vitamin D / blood
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / drug therapy*
  • Vitamin D Deficiency / epidemiology*
  • Vitamins / therapeutic use*

Substances

  • Vitamins
  • Vitamin D
  • Cholecalciferol
  • 25-hydroxyvitamin D