Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia

D Carcione; C Giele; L S Goggin; K S Kwan; D W Smith; G K Dowse; D B Mak; P Effler

Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia

Euro Surveill. 2010 Jul 15;15(28):19616.

Authors

D Carcione¹, C Giele, L S Goggin, K S Kwan, D W Smith, G K Dowse, D B Mak, P Effler

Affiliation

¹ Department of Health, Perth, Western Australia, Australia.

PMID: 20650055

Abstract

We conducted a prospective household transmission study to examine whether receipt of 2009 trivalent influenza vaccine (TIV) was associated with increased risk of influenza-like illness (ILI) among contacts of confirmed pandemic influenza A(H1N1) 2009 patients. In the week following onset of pandemic illness in a household member, 46 (15%) of 304 TIV-vaccinated contacts, and 174 (15%) of 1,162 unvaccinated contacts developed ILI (p=0.95). Receipt of 2009 TIV had no effect on one's risk of pandemic illness.

MeSH terms

Adolescent
Adult
Age Distribution
Child
Child, Preschool
Data Collection
Disease Outbreaks / prevention & control*
Family Characteristics*
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Influenza A Virus, H1N1 Subtype / immunology*
Influenza Vaccines / administration & dosage*
Influenza, Human / epidemiology
Influenza, Human / prevention & control
Influenza, Human / transmission*
Male
Middle Aged
Prospective Studies
Risk Factors
Sex Distribution
Vaccination / statistics & numerical data
Western Australia / epidemiology
Young Adult

Substances

Influenza Vaccines