Abstract
In patients participating in the Scandinavian Simvastatin Survival Study, cholesterol lowering with simvastatin reduced the incidence of carotid bruits and cerebrovascular events as well as new-onset or worsening of angina pectoris and intermittent claudication. These effects suggest that simvastatin may have a general antiatherosclerotic effect not limited to the coronary bed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Arteriosclerosis / complications
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Arteriosclerosis / prevention & control*
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Disease Progression
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Female
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Humans
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Hypolipidemic Agents / therapeutic use*
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Ischemia / etiology
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Ischemia / prevention & control*
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Male
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Middle Aged
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Randomized Controlled Trials as Topic
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Simvastatin / therapeutic use*
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Treatment Outcome
Substances
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Hypolipidemic Agents
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Simvastatin