Sleep disorders are common in the general population and even more so in clinical practice,
yet are relatively poorly understood by doctors and other health care practitioners. These …

In recent years there has been a shift toward greater recognition of the client’s role as an
active participant in psychotherapy. In 1994 Bergin and Garfield said,“Another important …

Objective: Melatonin, the hormone produced nocturnally by the pineal gland, serves as a
circadian time cue and sleep-anticipating signal in humans. With age, melatonin production …

Purpose A link between poor sleep quality and Alzheimer’s disease (AD) has recently been
suggested. Since endogenous melatonin levels are already reduced at preclinical AD stages…

Background Melatonin is extensively used in the USA in a non-regulated manner for sleep
disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for …

BackgroundCitalopram is a serotonin reuptake inhibitor which has been demonstrated to be
highly selective and with a superior tolerability profile to the classical tricyclic …

Objectives: The authors recently reported on efficacy and safety of prolonged-release
melatonin formulation (PRM; Circadin 2 mg) in elderly insomnia patients. The age cut-off for …

Objective Insomnia can be broadly defined as difficulty initiating or maintaining sleep, or sleep
that is not refreshing or of poor quality with negative effect on daytime function. Insomnia …

Background: The objective of this study was to evaluate the efficacy and tolerability of
citalopram in the long-term treatment of adult outpatients with panic disorder with or without …

BackgroundMajor depression is highly recurrent. Antidepressant maintenance treatment has
proven efficacy against recurrent depression.AimsComparison of prophylactic efficacy of …