Stargardt disease (STGD, also known as fundus flavimaculatus; FFM) is an autosomal recessive
retinal disorder characterized by a juvenile-onset macular dystrophy, alterations of the …

We conducted a genome-wide association study (GWAS) of breast cancer by genotyping
528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast …

Quality indicators have been developed throughout Europe primarily for use in hospitals,
but also increasingly for primary care. Both development and application are important but …

Over the past decade, clinical guidelines have increasingly become a familiar part of clinical
practice. Every day, clinical decisions at the bedside, rules of operation at hospitals and …

Chronic low-grade inflammation negatively impacts health and is associated with aging and
obesity, among other health outcomes. A large number of immune mediators are present in …

Autism spectrum disorders such as Rett syndrome (RTT) have been hypothesized to arise
from defects in experience-dependent synapse maturation. RTT is caused by mutations in …

MeCP2 is a methyl DNA–binding transcriptional regulator that contributes to the development
and function of CNS synapses; however, the requirement for MeCP2 in stimulus-regulated …

A semiconductor injection laser that differs in a fundamental way from diode lasers has
been demonstrated. It is built out of quantum semiconductor structures that were grown by …

Objectives The primary objective of these European evidence-based guidelines is to provide
a set of recommendations that can support existing and future national and international …

Age-related macular degeneration (AMD) is the leading cause of severe central visual
impairment among the elderly and is associated both with environmental factors such as smoking …