The “Grades of Recommendation, Assessment, Development, and Evaluation” (GRADE)
approach provides guidance for rating quality of evidence and grading strength of …

The objective of this study was to examine the relationship between autoimmune thyroid
disease and depression in perimenopausal women. Thyroid function [TSH, free T 4 , and …

The cause of pre-eclampsia is unknown, although a partner-specific immune maladaptation
might be involved. We compared rates of pre-eclampsia and gestational hypertension in …

Aim: Comorbidity is increasingly prevalent. Moreover, many different definitions and
interpretations of this phenomenon are used. Because of its social and clinical significance, it is …

In this article we discuss 3 hypotheses to attempt to understand why preventive measures
thus far studied with the aim of preventing (or delaying) the development of asthma have …

The CONSORT, QUORUM, and STARD checklists have made major contributions to the
standardization of reporting of clinical trials, systematic reviews, and diagnostic test studies. The …

Purpose: To evaluate the methodology of incidence studies of epilepsy and unprovoked
seizures and to assess the value of their findings by summarizing their results. Methods: A …

Seeking an evidence base for medicine is as old as medicine itself, but in the past decade
the concept of evidence based medicine has done a good job in focusing explicit attention on …

Introduction The supervision of medical residents is a key responsibility of attending doctors
in the clinical setting. Most attending doctors, however, are unfamiliar with the principles of …

Background . Factors related to physical health have been implicated in both normal and
pathological aging of cognitive abilities. To substantiate this notion, we studied existing …