Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies
Objective To systematically examine the design, reporting standards, risk of bias, and claims
of studies comparing the performance of diagnostic deep learning algorithms for medical …
of studies comparing the performance of diagnostic deep learning algorithms for medical …
[HTML][HTML] Redefining critical illness
…, EJ Giamarellos-Bourboulis, AC Gordon… - Nature medicine, 2022 - nature.com
Research and practice in critical care medicine have long been defined by syndromes,
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …
[HTML][HTML] Levosimendan: current data, clinical use and future development
…, LMA Heunks, PK Suominen, AC Gordon… - Heart, lung and …, 2013 - ncbi.nlm.nih.gov
… AC Gordon in conjunction with the Imperial Clinical Trials Unit) assessing the role of …
Fruhwald, AC Gordon and LMA Heunk. received limited grants and honoraria from Orion …
Fruhwald, AC Gordon and LMA Heunk. received limited grants and honoraria from Orion …
Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis
Importance Effective therapies for patients with coronavirus disease 2019 (COVID-19) are
needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced …
needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced …
Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report
Remap-Cap Investigators, AC Gordon, PR Mouncey… - Medrxiv, 2021 - medrxiv.org
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial
… Dr Gordon reported receiving grants from the NIHR and the NIHR Research Professorship;
nonfinancial support from the NIHR Clinical Research Network and the NIHR Imperial …
nonfinancial support from the NIHR Clinical Research Network and the NIHR Imperial …
[HTML][HTML] Vasopressin versus norepinephrine infusion in patients with septic shock
…, KR Walley, J Singer, AC Gordon… - … England Journal of …, 2008 - Mass Medical Soc
Background Vasopressin is commonly used as an adjunct to catecholamines to support blood
pressure in refractory septic shock, but its effect on mortality is unknown. We hypothesized …
pressure in refractory septic shock, but its effect on mortality is unknown. We hypothesized …
The artificial intelligence clinician learns optimal treatment strategies for sepsis in intensive care
Sepsis is the third leading cause of death worldwide and the main cause of mortality in
hospitals 1 , 2 – 3 , but the best treatment strategy remains uncertain. In particular, evidence …
hospitals 1 , 2 – 3 , but the best treatment strategy remains uncertain. In particular, evidence …
Y90 radioembolization significantly prolongs time to progression compared with chemoembolization in patients with hepatocellular carcinoma
Background & Aims Conventional transarterial chemoembolization (cTACE) is used to treat
patients with hepatocellular carcinoma (HCC). Radioembolization is a minimally invasive …
patients with hepatocellular carcinoma (HCC). Radioembolization is a minimally invasive …
[HTML][HTML] Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
…, P Hutton, TC Mills, A Rautanen, AC Gordon… - The Lancet …, 2016 - thelancet.com
Background Effective targeted therapy for sepsis requires an understanding of the
heterogeneity in the individual host response to infection. We investigated this heterogeneity by …
heterogeneity in the individual host response to infection. We investigated this heterogeneity by …