α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans
JT Brenna, N Salem Jr, AJ Sinclair… - … leukotrienes and essential …, 2009 - Elsevier
Blood levels of polyunsaturated fatty acids (PUFA) are considered biomarkers of status.
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain omega-3 …
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain omega-3 …
[HTML][HTML] Diagnosis and management of migraine in ten steps
…, HC Diener, DD Mitsikostas, AJ Sinclair… - Nature Reviews …, 2021 - nature.com
Migraine is a disabling primary headache disorder that directly affects more than one billion
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …
[HTML][HTML] European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention …
…, U Reuter, M Sanchez-Del-Rio, AJ Sinclair… - The journal of headache …, 2022 - Springer
Background A previous European Headache Federation (EHF) guideline addressed the use
of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway to …
of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway to …
Selection of threshold values in geochemical data using probability graphs
AJ Sinclair - Journal of geochemical exploration, 1974 - Elsevier
A method of choosing threshold values between anomalous and background geochemical
data, based on partitioning a cumulative probability plot of the data is described. The …
data, based on partitioning a cumulative probability plot of the data is described. The …
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
…, R Bruton, JA Ainsworth, AJ Sinclair… - The Journal of …, 2002 - journals.aai.org
The deterioration in immune function with aging is thought to make a major contribution to
the increased morbidity and mortality from infectious disease in old age. One aspect of …
the increased morbidity and mortality from infectious disease in old age. One aspect of …
Dietary intakes and food sources of omega‐6 and omega‐3 polyunsaturated fatty acids
BJ Meyer, NJ Mann, JL Lewis, GC Milligan, AJ Sinclair… - Lipids, 2003 - Wiley Online Library
Both n−6 and n−3 polyunsaturated fatty acids (PUFA) are recognized as essential nutrients
in the human diet, yet reliable data on population intakes are limited. The aim of the present …
in the human diet, yet reliable data on population intakes are limited. The aim of the present …
Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression
PB Adams, S Lawson, A Sanigorski, AJ Sinclair - Lipids, 1996 - Wiley Online Library
In this study of 20 moderately to severely depressed patients, diagnosed using current
research diagnostic criteria and excluding known bipolar affective disorder and reactive …
research diagnostic criteria and excluding known bipolar affective disorder and reactive …
Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services
AJ Sinclair, AJ Girling, AJ Bayer - Diabetes research and clinical practice, 2000 - Elsevier
Objective: To determine whether cognitive impairment is associated with changes in self-care
behaviour and use of health and social services in older subjects with diabetes mellitus. …
behaviour and use of health and social services in older subjects with diabetes mellitus. …
[HTML][HTML] Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function
…, MJ Pike, AH Turner, NJ Mann, AJ Sinclair - The American journal of …, 2003 - Elsevier
Background: Flavonoids may be partly responsible for some health benefits, including
antiinflammatory action and a decreased tendency for the blood to clot. An acute dose of flavanols …
antiinflammatory action and a decreased tendency for the blood to clot. An acute dose of flavanols …
Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial
Objective to investigate whether diets differing in fat content alter the gut microbiota and faecal
metabolomic profiles, and to determine their relationship with cardiometabolic risk factors …
metabolomic profiles, and to determine their relationship with cardiometabolic risk factors …