Quantitative signal detection using spontaneous ADR reporting
Quantitative methods are increasingly used to analyse spontaneous reports. We describe
the core concepts behind the most common methods, the proportional reporting ratio (PRR), …
the core concepts behind the most common methods, the proportional reporting ratio (PRR), …
[HTML][HTML] Eliciting public preferences for healthcare: a systematic review of techniques
M Ryan, DA Scott, C Reeves, A Bate… - Health technology …, 2001 - eprints.soton.ac.uk
BACKGROUND: Limited resources coupled with unlimited demand for healthcare mean that
decisions have to be made regarding the allocation of scarce resources across competing …
decisions have to be made regarding the allocation of scarce resources across competing …
Decision support methods for the detection of adverse events in post-marketing data
M Hauben, A Bate - Drug discovery today, 2009 - Elsevier
Spontaneous reporting is a crucial component of post-marketing drug safety surveillance
despite its significant limitations. The size and complexity of some spontaneous reporting …
despite its significant limitations. The size and complexity of some spontaneous reporting …
Use of discrete choice experiments to elicit preferences
M Ryan, A Bate, CJ Eastmond… - BMJ Quality & …, 2001 - qualitysafety.bmj.com
This paper considers the application of discrete choice experiments for eliciting preferences
in the delivery of health care. Drawing upon the results from a recently completed systematic …
in the delivery of health care. Drawing upon the results from a recently completed systematic …
Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study
DM Coulter, A Bate, RHB Meyboom, M Lindquist… - Bmj, 2001 - bmj.com
Objectives: To examine the relation between antipsychotic drugs and myocarditis and
cardiomyopathy. Design: Data mining using bayesian statistics implemented in a neural network …
cardiomyopathy. Design: Data mining using bayesian statistics implemented in a neural network …
A Bayesian neural network method for adverse drug reaction signal generation
A Bate, M Lindquist, IR Edwards, S Olsson… - European journal of …, 1998 - Springer
Objective: The database of adverse drug reactions (ADRs) held by the Uppsala Monitoring
Centre on behalf of the 47 countries of the World Health Organization (WHO) Collaborating …
Centre on behalf of the 47 countries of the World Health Organization (WHO) Collaborating …
A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions
EP van Puijenbroek, A Bate… - … and drug safety, 2002 - Wiley Online Library
Purpose A continuous systematic review of all combinations of drugs and suspected adverse
reactions (ADRs) reported to a spontaneous reporting system, is necessary to optimize …
reactions (ADRs) reported to a spontaneous reporting system, is necessary to optimize …
An experimentally supported model of the Bacillus subtilis global transcriptional regulatory network
ML Arrieta‐Ortiz, C Hafemeister, AR Bate… - Molecular systems …, 2015 - embopress.org
Organisms from all domains of life use gene regulation networks to control cell growth,
identity, function, and responses to environmental challenges. Although accurate global …
identity, function, and responses to environmental challenges. Although accurate global …
Shrinkage observed-to-expected ratios for robust and transparent large-scale pattern discovery
Large observational data sets are a great asset to better understand the effects of medicines
in clinical practice and, ultimately, improve patient care. For an empirical pattern in …
in clinical practice and, ultimately, improve patient care. For an empirical pattern in …
Vision‐based obstacle detection and navigation for an agricultural robot
This paper describes a vision‐based obstacle detection and navigation system for use as part
of a robotic solution for the sustainable intensification of broad‐acre agriculture. To be cost…
of a robotic solution for the sustainable intensification of broad‐acre agriculture. To be cost…