[HTML][HTML] The heteromeric organic solute transporter α-β, Ostα-Ostβ, is an ileal basolateral bile acid transporter

…, M Hubbert, J Haywood, AL Craddock… - Journal of Biological …, 2005 - ASBMB
Bile acids are transported across the ileal enterocyte brush border membrane by the well
characterized apical sodium-dependent bile acid transporter (Asbt) Slc10a2; however, the …

[HTML][HTML] Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter.

MH Wong, P Oelkers, AL Craddock… - Journal of Biological …, 1994 - Elsevier
Active uptake of bile acids from the lumen of the small intestine is mediated by an ileal Na(+)-dependent
bile acid transport system. To identify components of this transport system, an …

Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter

AL Craddock, MW Love, RW Daniel… - American Journal …, 1998 - journals.physiology.org
The enterohepatic circulation of bile acids is maintained by Na + -dependent transport
mechanisms. To better understand these processes, a full-length human ileal Na + -bile acid …

[HTML][HTML] Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice

PA Dawson, J Haywood, AL Craddock, M Wilson… - Journal of Biological …, 2003 - ASBMB
The ileal apical sodium bile acid cotransporter participates in the enterohepatic circulation
of bile acids. In patients with primary bile acid malabsorption, mutations in the ileal bile acid …

The organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis

A Rao, J Haywood, AL Craddock… - Proceedings of the …, 2008 - National Acad Sciences
The apical sodium-dependent bile acid transporter (Asbt) is responsible for transport across
the intestinal brush border membrane; however, the carrier(s) responsible for basolateral …

Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12–13.1

…, SC Fossey, SJ Mihic, AL Craddock… - Molecular genetics and …, 2001 - Elsevier
We have carried out a detailed sequence and functional analysis of a novel human facilitative
glucose transporter, designated GLUT10, located in the Type 2 diabetes-linked region of …

APOL1 renal-risk variants induce mitochondrial dysfunction

…, JA Snipes, MS Bharadwaj, AL Craddock… - Journal of the …, 2017 - journals.lww.com
APOL1 G1 and G2 variants facilitate kidney disease in blacks. To elucidate the pathways
whereby these variants contribute to disease pathogenesis, we established HEK293 cell lines …

Expression, transport properties, and chromosomal location of organic anion transporter subtype 3

HC Walters, AL Craddock… - American Journal …, 2000 - journals.physiology.org
The rat and mouse organic anion-transporting polypeptides (oatp) subtype 3 (oatp3) were
cloned to further define components of the intestinal bile acid transport system. In transfected …

[HTML][HTML] APOL1 kidney-risk variants induce mitochondrial fission

…, JW Chou, AK Hemal, S Petrovic, AL Craddock… - Kidney international …, 2020 - Elsevier
Introduction APOL1 G1 and G2 nephropathy-risk variants cause mitochondrial dysfunction
and contribute to kidney disease. Analyses were performed to determine the genetic …

Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity

…, K Holl, O Seshie, AL Craddock… - Physiological …, 2022 - journals.physiology.org
Transcriptomic analysis in metabolically active tissues allows a systems genetics approach
to identify causal genes and networks involved in metabolic disease. Outbred …