[HTML][HTML] Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
…, TD Shuster, ME Frantz, AE Spooner… - … England Journal of …, 1995 - Mass Medical Soc
Background Metastatic prostate cancer is a leading cause of cancer-related death in men.
The rate of response to androgen ablation is high, but most patients relapse as a result of the …
The rate of response to androgen ablation is high, but most patients relapse as a result of the …
[HTML][HTML] Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms
Type 2 diabetes (T2D) affects Latinos at twice the rate seen in populations of European
descent. We recently identified a risk haplotype spanning SLC16A11 that explains ∼20% of the …
descent. We recently identified a risk haplotype spanning SLC16A11 that explains ∼20% of the …
IgG4‐related systemic disease and lymphoplasmacytic aortitis
…, A Hilgenberg, A Spooner… - … : Official Journal of …, 2009 - Wiley Online Library
We describe herein a patient who developed a dissection of the ascending aorta in the
setting of IgG4‐related systemic disease, linking IgG4‐related systemic disease with a newly‐…
setting of IgG4‐related systemic disease, linking IgG4‐related systemic disease with a newly‐…
Comparison of positron emission tomography measurement of adenosine-stimulated absolute myocardial blood flow versus relative myocardial tracer content for …
MM Hajjiri, MB Leavitt, H Zheng, AE Spooner… - JACC: Cardiovascular …, 2009 - jacc.org
Objectives : This study tests the hypothesis that absolute measurement of adenosine (Ado)-stimulated
myocardial blood flow (MBFado) is superior to measurement of relative tracer …
myocardial blood flow (MBFado) is superior to measurement of relative tracer …
The comprehension skills of children learning English as an additional language
…, JM Kelly, HE Whiteley, A Spooner - British Journal of …, 2009 - Wiley Online Library
Background Data from national test results suggests that children who are learning English
as an additional language (EAL) experience relatively lower levels of educational attainment …
as an additional language (EAL) experience relatively lower levels of educational attainment …
[HTML][HTML] Promoting and protecting public health: how the European Union pharmacovigilance system works
A Santoro, G Genov, A Spooner, J Raine, P Arlett - Drug safety, 2017 - Springer
This article provides an overview of the European Union pharmacovigilance system resulting
from the rationalisation and strengthening delivered through the implementation of the …
from the rationalisation and strengthening delivered through the implementation of the …
Direct extubation onto high-flow nasal cannulae post-cardiac surgery versus standard treatment in patients with a BMI≥ 30: a randomised controlled trial
Purpose Patients with a body mass index (BMI) ≥30 kg/m 2 experience more severe atelectasis
following cardiac surgery than those with normal BMI and its resolution is slower. This …
following cardiac surgery than those with normal BMI and its resolution is slower. This …
Proactively managing the risk of marketed drugs: experience with the EMA Pharmacovigilance Risk Assessment Committee
…, K Blake, N Wathion, JM Dogne, A Spooner… - Nature reviews Drug …, 2014 - nature.com
Although signal evaluations usually focus on one or a small number of specific ADRs, more
global risk or benefit–risk assessments of a drug or group of drugs take place through …
global risk or benefit–risk assessments of a drug or group of drugs take place through …
Nasal high flow oxygen therapy in patients with COPD reduces respiratory rate and tissue carbon dioxide while increasing tidal and end-expiratory lung volumes: a …
Patients with COPD using long-term oxygen therapy (LTOT) over 15 h per day have improved
outcomes. As inhalation of dry cold gas is detrimental to mucociliary clearance, humidified …
outcomes. As inhalation of dry cold gas is detrimental to mucociliary clearance, humidified …
Measurement of the frequency and source of interruptions occurring during bedside nursing handover in the intensive care unit: an observational study
Background Effective clinical handover involves the communication of relevant patient
information from one care provider to another and is critical in ensuring patient safety. …
information from one care provider to another and is critical in ensuring patient safety. …