Background Accurate rapid diagnostic tests for SARS‐CoV‐2 infection would be a useful tool
to help manage the COVID‐19 pandemic. Testing strategies that use rapid antigen tests to …

Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. …

Background COVID‐19 illness is highly variable, ranging from infection with no symptoms
through to pneumonia and life‐threatening consequences. Symptoms such as fever, cough, or …

RESEARCH Page 1 RESEARCH Diagnostic value of laboratory tests in identifying serious
infections in febrile children: systematic review Ann Van den Bruel, academic clinical lecturer,…

Background Our aim was to identify which clinical features have value in confirming or
excluding the possibility of serious infection in children presenting to ambulatory care settings in …

Background The respiratory illness caused by SARS‐CoV‐2 infection continues to present
diagnostic challenges. Our 2020 edition of this review showed thoracic (chest) imaging to be …

Western European health systems are not keeping pace with changes in child health needs.
Non-communicable diseases are increasingly common causes of childhood illness and …

Objective To investigate the basis and added value of clinicians’ “gut feeling” that infections
in children are more serious than suggested by clinical assessment. Design Observational …

Objective Despite the growing number of point-of-care (POC) tests available, little research
has assessed primary care clinician need for such tests. We therefore aimed to determine …

Background Serious infections in children (sepsis, meningitis, pneumonia, pyelonephritis,
osteomyelitis, and cellulitis) are associated with considerable mortality and morbidity. In …