[HTML][HTML] Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene
Background Macrosomia is associated with considerable neonatal and maternal morbidity.
Factors that predict macrosomia are poorly understood. The increased rate of macrosomia in …
Factors that predict macrosomia are poorly understood. The increased rate of macrosomia in …
Prevalence of vascular complications among patients with glucokinase mutations and prolonged, mild hyperglycemia
AM Steele, BM Shields, KJ Wensley, K Colclough… - Jama, 2014 - jamanetwork.com
Importance Glycemic targets in diabetes have been developed to minimize complication risk.
Patients with heterozygous, inactivating glucokinase (GCK)mutations have mild fasting …
Patients with heterozygous, inactivating glucokinase (GCK)mutations have mild fasting …
Recognition and management of individuals with hyperglycemia because of a heterozygous glucokinase mutation
AJ Chakera, AM Steele, AL Gloyn, MH Shepherd… - Diabetes …, 2015 - Am Diabetes Assoc
Glucokinase–maturity-onset diabetes of the young (GCK-MODY), also known as MODY2, is
caused by heterozygous inactivating mutations in the GCK gene. GCK gene mutations are …
caused by heterozygous inactivating mutations in the GCK gene. GCK gene mutations are …
A randomised trial investigating guided self-help to reduce perfectionism and its impact on bulimia nervosa: A pilot study
AL Steele, TD Wade - Behaviour Research and Therapy, 2008 - Elsevier
AIM: The purpose of the present study was to evaluate reducing perfectionism as a potential
treatment target for individuals with Bulimia Nervosa (BN). METHOD: Forty-eight individuals …
treatment target for individuals with Bulimia Nervosa (BN). METHOD: Forty-eight individuals …
[HTML][HTML] Use of HbA1c in the identification of patients with hyperglycaemia caused by a glucokinase mutation: observational case control studies
Aims HaemoglobinA1c (HbA1c) is recommended for diabetes diagnosis but fasting plasma
glucose (FPG) has been useful for identifying patients with glucokinase (GCK) mutations …
glucose (FPG) has been useful for identifying patients with glucokinase (GCK) mutations …
Motivational interviewing for modifying diabetes risk: a randomised controlled trial
…, L O'Loughlin, S Holland, J Piper, A Steele… - British Journal of …, 2008 - bjgp.org
Background Around 10–15% of adults aged over 40 years have pre-diabetes, which carries
a high risk of progression to type 2 diabetes. Intensive lifestyle intervention reduces …
a high risk of progression to type 2 diabetes. Intensive lifestyle intervention reduces …
Psycho-education and group cognitive-behavioural therapy for clinical perfectionism: A case-series evaluation
AL Steele, S Waite, SJ Egan, J Finnigan… - Behavioural and …, 2013 - cambridge.org
Background: Research indicates that psycho-education and cognitive behavioural interventions
can reduce perfectionism but to date no group treatments have been examined. Aims: …
can reduce perfectionism but to date no group treatments have been examined. Aims: …
[HTML][HTML] Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young
…, C Buettger, HAJ Castleden, AM Steele… - Journal of Biological …, 2005 - ASBMB
Glucokinase (GCK) serves as the pancreatic glucose sensor. Heterozygous inactivating GCK
mutations cause hyperglycemia, whereas activating mutations cause hypoglycemia. We …
mutations cause hyperglycemia, whereas activating mutations cause hypoglycemia. We …
[HTML][HTML] People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population
…, L Parkinson, TM Frayling, A Steele… - European Journal of …, 2012 - nature.com
There is a great deal of interest in a fine-scale population structure in the UK, both as a
signature of historical immigration events and because of the effect population structure may …
signature of historical immigration events and because of the effect population structure may …
Interarm blood pressure difference in people with diabetes: measurement and vascular and mortality implications: a cohort study
OBJECTIVE Differences in blood pressure between arms are associated with vascular
disease and increased mortality; this has not been reported in diabetes. We explored these …
disease and increased mortality; this has not been reported in diabetes. We explored these …