Adjuvant psychological therapy for patients with cancer: a prospective randomised trial.
…, JD Baruch, M Watson, BM Robertson, A Mason… - British Medical …, 1992 - bmj.com
OBJECTIVE--To determine the effect of adjuvant psychological therapy on the quality of life
of patients with cancer. DESIGN--Prospective randomised controlled trial comparing the …
of patients with cancer. DESIGN--Prospective randomised controlled trial comparing the …
Topical treatments for chronic plaque psoriasis
Background Chronic plaque psoriasis is the most common type of psoriasis, and it is
characterised by redness, thickness, and scaling. First‐line management of chronic plaque …
characterised by redness, thickness, and scaling. First‐line management of chronic plaque …
Structural basis for iron piracy by pathogenic Neisseria
Neisseria are obligate human pathogens causing bacterial meningitis, septicaemia and
gonorrhoea. Neisseria require iron for survival and can extract it directly from human transferrin …
gonorrhoea. Neisseria require iron for survival and can extract it directly from human transferrin …
[HTML][HTML] The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding
…, C Vonrhein, MA Rould, SJ Everse, AB Mason… - Journal of Biological …, 2006 - ASBMB
Serum transferrin reversibly binds iron in each of two lobes and delivers it to cells by a
receptor-mediated, pH-dependent process. The binding and release of iron result in a large …
receptor-mediated, pH-dependent process. The binding and release of iron result in a large …
Two High-Resolution Crystal Structures of the Recombinant N-Lobe of Human Transferrin Reveal a Structural Change Implicated in Iron Release,
The N-lobe of human serum transferrin (hTF/2N) has been expressed in baby hamster
kidney cells and crystallized in both orthorhombic (P2 1 2 1 2 1 ) and tetragonal (P4 1 2 1 2) …
kidney cells and crystallized in both orthorhombic (P2 1 2 1 2 1 ) and tetragonal (P4 1 2 1 2) …
Etanercept and efalizumab for the treatment of psoriasis: a systematic review.
OBJECTIVES: To evaluate the clinical effectiveness, safety, tolerability and cost-effectiveness
of etanercept and efalizumab for the treatment of moderate to severe chronic plaque …
of etanercept and efalizumab for the treatment of moderate to severe chronic plaque …
The long history of iron in the Universe and in health and disease
BACKGROUND: Not long after the Big Bang, iron began to play a central role in the Universe
and soon became mired in the tangle of biochemistry that is the prima essentia of life. …
and soon became mired in the tangle of biochemistry that is the prima essentia of life. …
Evolution of the transferrin family: conservation of residues associated with iron and anion binding
…, H Perri, PJ Halbrooks, AB Mason - … and Physiology Part B …, 2005 - Elsevier
The transferrin family spans both vertebrates and invertebrates. It includes serum transferrin,
ovotransferrin, lactoferrin, melanotransferrin, inhibitor of carbonic anhydrase, saxiphilin, the …
ovotransferrin, lactoferrin, melanotransferrin, inhibitor of carbonic anhydrase, saxiphilin, the …
How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH
…, ND Chasteen, SJ Everse, AB Mason - Proceedings of the …, 2011 - National Acad Sciences
Delivery of iron to cells requires binding of two iron-containing human transferrin (hTF)
molecules to the specific homodimeric transferrin receptor (TFR) on the cell surface. Through …
molecules to the specific homodimeric transferrin receptor (TFR) on the cell surface. Through …
Transferrin-mediated cellular iron delivery
AN Luck, AB Mason - Current topics in membranes, 2012 - Elsevier
Essential to iron homeostasis is the transport of iron by the bilobal protein human serum
transferrin (hTF). Each lobe (N- and C-lobe) of hTF forms a deep cleft which binds a single Fe 3+ …
transferrin (hTF). Each lobe (N- and C-lobe) of hTF forms a deep cleft which binds a single Fe 3+ …