The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of
anonymised medical records from general practitioners, with coverage of over 11.3 million …

Atrial fibrillation (AF) carries an increased risk of ischaemic stroke, and oral anticoagulation
with warfarin can reduce this risk. The objective of this study was to evaluate the association …

Purpose Large electronic datasets are increasingly being used to evaluate healthcare delivery.
The aim of this study was to compare information held by cancer registries with that of the …

The effects of low persistence on fracture risk have not been fully addressed. The objectives
of this study were to describe the persistence and compliance with bisphosphonates and to …

Background There is a concern that topical tacrolimus and pimecrolimus, indicated for
second-line treatment of atopic dermatitis, may increase the risk of lymphoma and skin cancer, …

Purpose It is not clear whether all deaths are recorded in the Clinical Practice Research
Datalink (CPRD) or how accurate a recorded date of death is. Individual‐level linkage with …

Little is known about whether the incidence of symptoms of fatigue presented in primary care,
and the consequent diagnoses made, change over time. The UK General Practice …

Objectives Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant
health burden. The aim of this study was to characterise patients with recently diagnosed …

Background: The use of thiazolidinediones (TZDs) has been associated with increased
fracture risks. Our aim was to estimate the risk of fracture with TZDs in three different healthcare …

Objectives and setting Conflicting results from studies using electronic health records to
evaluate the associations between type 2 diabetes and cancer fuel concerns regarding potential …