Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

…, AM Fein, WA Knaus, RMH Schein, WJ Sibbald - Chest, 1992 - Elsevier
An American College of Chest Physicians/Society of Critical Care Medicine Consensus
Conference was held in Northbrook in August 1991 with the goal of agreeing on a set of …

Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome

…, GR Bernard, CL Sprung, WJ Sibbald - Critical care …, 1995 - journals.lww.com
Objective To develop an objective scale to measure the severity of the multiple organ
dysfunction syndrome as an outcome in critical illness. Design

The P-loop—a common motif in ATP-and GTP-binding proteins

M Saraste, PR Sibbald, A Wittinghofer - Trends in biochemical sciences, 1990 - cell.com
Many ATP-and GTP-binding proteins have a phosphate-binding loop (P-loop), the primary
structure of which typically consists of a glycine-rich sequence followed by a conserved lysine …

International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods

…, EA Mitchell, N Pearce, B Sibbald… - European respiratory …, 1995 - Eur Respiratory Soc
The aetiology of asthma and allergic disease remains poorly understood, despite considerable
research. The International Study of Asthma and Allergies in Childhood (ISAAC), was …

Defining comorbidity: implications for understanding health and health services

JM Valderas, B Starfield, B Sibbald… - The Annals of Family …, 2009 - Annals Family Med
Comorbidity is associated with worse health outcomes, more complex clinical management,
and increased health care costs. There is no agreement, however, on the meaning of the …

Wound bed preparation: a systematic approach to wound management

GS Schultz, RG Sibbald, V Falanga… - Wound repair and …, 2003 - Wiley Online Library
The healing process in acute wounds has been extensively studied and the knowledge
derived from these studies has often been extrapolated to the care of chronic wounds, on the …

Substitution of doctors by nurses in primary care

…, J Braspenning, R Grol, B Sibbald - Cochrane database …, 2005 - cochranelibrary.com
Background Demand for primary care services has increased in developed countries due to
population ageing, rising patient expectations, and reforms that shift care from hospitals to …

Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood

…, S Montefort, N Pearce, J Shah, B Sibbald… - Journal of allergy and …, 1999 - Elsevier
Background: Little is known about the prevalence of atopic eczema outside Northern Europe.
Objectives: We sought to describe the magnitude and variation in the prevalence of atopic …

A bioassay for true metabolizable energy in feedingstuffs

IR Sibbald - Poultry science, 1976 - Elsevier
In 12 experiments with SCWL roosters it was shown that for each of 12 feedingstuffs there
was a linear relationship between feed input and the amount of energy voided as excreta. In …

Understanding controlled trials. Why are randomised controlled trials important?

B Sibbald, M Roland - BMJ: British Medical Journal, 1998 - ncbi.nlm.nih.gov
Randomised controlled trials are the most rigorous way of determining whether a cause-effect
relation exists between treatment and outcome and for assessing the cost effectiveness of …