Continued improvements in cancer therapies have increased the number of long-term cancer
survivors. Radiation therapy remains one of the primary treatment modalities with about 60…

Current therapies for nerve regeneration within injured tissues have had limited success due
to complicated neural anatomy and inhibitory barriers in situ. Recent advancements in 3D …

Aging and age-related neurodegeneration are both associated with the accumulation of
unfolded and abnormally folded proteins, highlighting the importance of protein homeostasis (…

The conformational change of a host protein, PrP C , into a disease-associated isoform, PrP
Sc , appears to play a critical role in the pathogenesis of prion diseases such as Creutzfeldt–…

Most cancer cells are characterized by aneuploidy, an abnormal number of chromosomes.
We have identified a clue to the mechanistic origins of aneuploidy through integrative …

Immune exclusion predicts poor patient outcomes in multiple malignancies, including triple-negative
breast cancer (TNBC) 1 . The extracellular matrix (ECM) contributes to immune …

Object Accurate discrimination between tumor and normal tissue is crucial for optimal tumor
resection. Qualitative fluorescence of protoporphyrin IX (PpIX), synthesized endogenously …

Object The aim of this study was to investigate the relationships between intraoperative
fluorescence, features on MR imaging, and neuropathological parameters in 11 cases of newly …

… Harris,3,4 Lyle W. Ostrow,3,5 Hemali Phatnani,2,3 John Ravits,3,6 Josh Dubnau,3,7,8 and
Molly … Harris. Additional information regarding the principal investigators of the NYGC ALS …

Glia constitute 90% of cells in the human nervous system, but relatively little is known about
their functions. We have been focusing on the potential synaptic roles of glia in the CNS. We …