[PDF][PDF] Consensus development methods, and their use in clinical guideline development.
…, DL Lamping, CM McKee… - Health …, 1998 - researchonline.lshtm.ac.uk
NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced
cost of£ 100 for each volume (normally comprising 30–40 titles). The commercial …
cost of£ 100 for each volume (normally comprising 30–40 titles). The commercial …
NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma
The NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome is an
immunological sensor that detects a wide range of microbial- and host-derived signals. …
immunological sensor that detects a wide range of microbial- and host-derived signals. …
[HTML][HTML] Elexacaftor–tezacaftor–ivacaftor for cystic fibrosis with a single Phe508del allele
…, F Vermeulen, G Marigowda, CM McKee… - … England Journal of …, 2019 - Mass Medical Soc
Background Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis
transmembrane conductance regulator (CFTR) protein, and nearly 90% of patients have at …
transmembrane conductance regulator (CFTR) protein, and nearly 90% of patients have at …
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.
CM McKee, MB Penno, M Cowman… - The Journal of …, 1996 - Am Soc Clin Investig
Hyaluronan (HA) is a glycosaminoglycan constituent of extracellular matrix. In its native form
HA exists as a high molecular weight polymer, but during inflammation lower molecular …
HA exists as a high molecular weight polymer, but during inflammation lower molecular …
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double …
Background Cystic fibrosis transmembrane conductance regulator (CFTR) modulators correct
the basic defect caused by CFTR mutations. Improvements in health outcomes have been …
the basic defect caused by CFTR mutations. Improvements in health outcomes have been …
Measuring the health of nations: updating an earlier analysis
We compared trends in deaths considered amenable to health care before age seventy-five
between 1997–98 and 2002–03 in the United States and in eighteen other industrialized …
between 1997–98 and 2002–03 in the United States and in eighteen other industrialized …
[HTML][HTML] VX-445–tezacaftor–ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles
…, SM Rowe, LA Sass, E Tullis, CM McKee… - New england journal …, 2018 - Mass Medical Soc
Background VX-445 is a next-generation cystic fibrosis transmembrane conductance regulator
(CFTR) corrector designed to restore Phe508del CFTR protein function in patients with …
(CFTR) corrector designed to restore Phe508del CFTR protein function in patients with …
Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages.
PW Noble, CM McKee, M Cowman… - The Journal of …, 1996 - rupress.org
Macrophages play an important role in the acute tissue inflammatory response through the
release of cytokines and growth factors in response to stimuli such as lipopolysaccharide (…
release of cytokines and growth factors in response to stimuli such as lipopolysaccharide (…
[HTML][HTML] VX-659–tezacaftor–ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles
…, E Tullis, A Uluer, CM McKee… - New england journal …, 2018 - Mass Medical Soc
Background The next-generation cystic fibrosis transmembrane conductance regulator (CFTR)
corrector VX-659, in triple combination with tezacaftor and ivacaftor (VX-659–tezacaftor–…
corrector VX-659, in triple combination with tezacaftor and ivacaftor (VX-659–tezacaftor–…
[HTML][HTML] Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor κB-dependent mechanism
CM McKee, CJ Lowenstein, MR Horton, J Wu… - Journal of Biological …, 1997 - ASBMB
Activated macrophages play a critical role in controlling chronic tissue inflammation through
the release of a variety of mediators including cytokines, chemokines, growth factors, active …
the release of a variety of mediators including cytokines, chemokines, growth factors, active …